[HTML][HTML] Prognostic impact of KRAS G12C mutation in patients with NSCLC: results from the European Thoracic Oncology Platform Lungscape Project
Introduction KRAS mutations, the most frequent gain-of-function alterations in NSCLC, are
currently emerging as potential predictive therapeutic targets. The role of KRAS-G12C …
currently emerging as potential predictive therapeutic targets. The role of KRAS-G12C …
Phase 2 study of copanlisib in combination with gemcitabine and cisplatin in advanced biliary tract cancers
Background Biliary tract cancer (BTC) has a poor prognosis despite treatment with first‐line
gemcitabine and cisplatin. In BTC, PI3K/AKT pathway activation has been shown to increase …
gemcitabine and cisplatin. In BTC, PI3K/AKT pathway activation has been shown to increase …
MiR-421 promotes lipid metabolism by targeting PTEN via activating PI3K/AKT/mTOR pathway in non-small cell lung cancer
YJ Xu, RS Wei, XH Li, Q Li, JR Yu, XF Zhuang - Epigenomics, 2022 - Taylor & Francis
Aims: We aim to investigate the effects of miR-421 on lipid metabolism in non-small cell lung
cancer (NSCLC). Methods: The miR-421 expression and PTEN mRNA level in tumor …
cancer (NSCLC). Methods: The miR-421 expression and PTEN mRNA level in tumor …
Prognostic impact of tumour mutational burden in resected stage I and II lung adenocarcinomas from a European Thoracic Oncology Platform Lungscape cohort
Background The primary objective of this study is to evaluate tumor mutational burden
(TMB), its associations with selected clinicopathological and molecular characteristics as …
(TMB), its associations with selected clinicopathological and molecular characteristics as …
Precise definition of PTEN C-terminal epitopes and its implications in clinical oncology
J Mingo, S Luna, A Gaafar, CE Nunes-Xavier… - NPJ precision …, 2019 - nature.com
Anti-PTEN monoclonal antibodies (mAb) are arising as important tools for
immunohistochemistry (IHC) and protein quantification routine analysis in clinical oncology …
immunohistochemistry (IHC) and protein quantification routine analysis in clinical oncology …
Assessment of RANK/RANK-L prevalence and clinical significance in NSCLC European Thoracic Oncology Platform Lungscape cohort and SPLENDOUR …
Background The primary objective of this study is to evaluate the clinical significance of
RANK/L expression, in both a retrospective cohort of surgically resected stage I-III NSCLC …
RANK/L expression, in both a retrospective cohort of surgically resected stage I-III NSCLC …
СПОСОБ ОЦЕНКИ ЭНДОМЕТРИАЛЬНОЙ ДИСФУНКЦИИ У ЖЕНЩИН С ПЕРВИЧНЫМ ЭНДОМЕТРИОЗ-АССОЦИИРОВАННЫМ БЕСПЛОДИЕМ
АА ГРИШКИНА, ГН ЧИСТЯКОВА, НВ БАШМАКОВА… - 2020 - elibrary.ru
Изобретение относится к области медицины, в частности к патоморфологии,
акушерству и гинекологии. Предложен способ оценки рецептивности эндометрия в …
акушерству и гинекологии. Предложен способ оценки рецептивности эндометрия в …