Abstract Purpose of Review Mitochondria play various roles that are important for cell
function and survival; therefore, significant mitochondrial dysfunction may have chronic …

Environmental pollution is a major cause of global mortality and burden of disease. All
chemical pollution forms together may be responsible for up to 12 million annual excess …

Background: Cells respond to environmental stressors through several key pathways,
including response to reactive oxygen species (ROS), nutrient and ATP sensing, DNA …

Abstract PM 2.5 (particulate matter≤ 2.5 µm in aerodynamic diameter) refers to atmospheric
particulate matter (PM) with an aerodynamic diameter of equal and less than 2.5 µm that …

Exposure to ambient fine particulate matter (PM 2.5) is associated with neurodegenerative
diseases. Mitochondrion is key to brain degeneration. However, the underlying mechanism …

Background Little is known about the association between air pollution exposure and
sarcopenia in Asia. We aimed to investigate the associations of indoor solid fuel use and …

The mitochondrial DNA (mtDNA) is a closed circular molecule that encodes, in humans, 13
polypeptides components of the oxidative phosphorylation complexes. Integrity of the …

Background: Telomere length and mitochondrial DNA (mtDNA) content are markers of aging
and aging-related diseases. There is inconclusive evidence concerning the mechanistic …

Research efforts in the past decades have provided insight into the adverse health effects of
air pollution exposure. Exposure to airborne particulate matter is known to impair the …

The immune system is one of the primary targets of airborne particulate matter. Recent
evidence suggests that mitochondria lie at the center of particulate matter-induced …