The impact of stress on brain health begins in the womb. Both animal and human studies
have found that prenatal maternal stress affects the brain and behavior of the offspring …

Serotonin regulates a wide variety of brain functions and behaviors. Here, we synthesize
previous findings that serotonin regulates executive function, sensory gating, and social …

Parvalbumin inhibitory interneurons (PVIs) are crucial for maintaining proper
excitatory/inhibitory balance and high-frequency neuronal synchronization. Their activity …

Accumulating evidence points to altered GABAergic parvalbumin-expressing interneurons
and impaired myelin/axonal integrity in schizophrenia. Both findings could be due to …

Human neurodevelopment requires the organization of neural elements into complex
structural and functional networks called the connectome. Emerging data suggest that …

The discovery, approximately 15 years ago, that cortical GABA ergic interneurons originate
outside the pallium has revolutionized our understanding of the development of the cerebral …

Schizophrenia is a neurodevelopmental disorder reflecting a convergence of genetic risk
and early life stress. The slow progression to first psychotic episode represents both a …

When considering neurodevelopmental disorders (NDDs), Schizophrenia (SZ) and Autism
Spectrum Disorder (ASD) are considered to be among the most severe in term of …

The prefrontal cortex (PFC), seat of the highest-order cognitive functions, constitutes a
conglomerate of highly specialized brain areas and has been implicated to have a role in …

Risk for neuropsychiatric disorders is complex and includes an individual's internal genetic
endowment and their environmental experiences and exposures. Embryonic development …