Artificial general intelligence for radiation oncology

C Liu, Z Liu, J Holmes, L Zhang, L Zhang, Y Ding… - Meta-radiology, 2023 - Elsevier
The emergence of artificial general intelligence (AGI) is transforming radiation oncology. As
prominent vanguards of AGI, large language models (LLMs) such as GPT-4 and PaLM 2 can …

Proton versus photon radiation therapy: A clinical review

Z Chen, MM Dominello, MC Joiner… - Frontiers in …, 2023 - frontiersin.org
While proton radiation therapy offers substantially better dose distribution characteristics
than photon radiation therapy in certain clinical applications, data demonstrating a …

Deep‐learning based fast and accurate 3D CT deformable image registration in lung cancer

Y Ding, H Feng, Y Yang, J Holmes, Z Liu, D Liu… - Medical …, 2023 - Wiley Online Library
Abstract Background Deformable Image Registration (DIR) is an essential technique
required in many applications of radiation oncology. However, conventional DIR …

Proton beam therapy reduces the risk of severe radiation-induced lymphopenia during chemoradiotherapy for locally advanced non-small cell lung cancer: A …

N Kim, JM Noh, W Lee, B Park, H Park, JY Park… - Radiotherapy and …, 2021 - Elsevier
Hypothesis We investigated differences in severe radiation-induced lymphopenia (SRL)
after pencil beam scanning proton therapy (PBSPT) or intensity-modulated (photon) …

Beam mask and sliding window‐facilitated deep learning‐based accurate and efficient dose prediction for pencil beam scanning proton therapy

L Zhang, JM Holmes, Z Liu, SA Vora, TT Sio… - Medical …, 2024 - Wiley Online Library
Background Accurate and efficient dose calculation is essential for on‐line adaptive
planning in proton therapy. Deep learning (DL) has shown promising dose prediction results …

Intensity‐modulated proton therapy (IMPT) interplay effect evaluation of asymmetric breathing with simultaneous uncertainty considerations in patients with non‐small …

J Shan, Y Yang, SE Schild, TB Daniels… - Medical …, 2020 - Wiley Online Library
Purpose Intensity‐modulated proton therapy (IMPT) is sensitive to uncertainties from patient
setup and proton beam range, as well as interplay effect. In addition, respiratory motion may …

Exploratory study of seed spots analysis to characterize dose and linear‐energy‐transfer effect in adverse event initialization of pencil‐beam‐scanning proton therapy

Y Yang, SH Patel, J Bridhikitti, WW Wong… - Medical …, 2022 - Wiley Online Library
Background Both dose and linear energy transfer (LET) could play a substantial role in
adverse event (AE) initialization of cancer patients treated with pencil‐beam‐scanning …

Benchmarking a foundation large language model on its ability to relabel structure names in accordance with the american association of physicists in medicine task …

J Holmes, L Zhang, Y Ding, H Feng, Z Liu, T Liu… - Practical Radiation …, 2024 - Elsevier
Purpose To introduce the concept of using large language models (LLMs) to relabel
structure names in accordance with the American Association of Physicists in Medicine Task …

Fast Monte Carlo dose calculation in proton therapy

J Holmes, H Feng, L Zhang, MK Fix… - Physics in Medicine & …, 2024 - iopscience.iop.org
This article examines the critical role of fast Monte Carlo (MC) dose calculations in
advancing proton therapy techniques, particularly in the context of increasing treatment …

Modelling small block aperture in an in-house developed GPU-accelerated Monte Carlo-based dose engine for pencil beam scanning proton therapy

H Feng, JM Holmes, SA Vora, JB Stoker… - Physics in Medicine …, 2024 - iopscience.iop.org
Purpose. To enhance an in-house graphic-processing-unit accelerated virtual particle (VP)-
based Monte Carlo (MC) proton dose engine (VPMC) to model aperture blocks in both dose …