Colloquium: Criticality and dynamical scaling in living systems

MA Munoz - Reviews of Modern Physics, 2018 - APS
A celebrated and controversial hypothesis suggests that some biological systems—parts,
aspects, or groups of them—may extract important functional benefits from operating at the …

[HTML][HTML] Networks behind the morphology and structural design of living systems

M Gosak, M Milojević, M Duh, K Skok, M Perc - Physics of Life Reviews, 2022 - Elsevier
Technological advances in imaging techniques and biometric data acquisition have enabled
us to apply methods of network science to study the morphology and structural design of …

Mechanobiology of organelles: illuminating their roles in mechanosensing and mechanotransduction

S Phuyal, P Romani, S Dupont, H Farhan - Trends in Cell Biology, 2023 - cell.com
Mechanobiology studies the mechanisms by which cells sense and respond to physical
forces, and the role of these forces in shaping cells and tissues themselves …

Single organelle function and organization as estimated from Arabidopsis mitochondrial proteomics

P Fuchs, N Rugen, C Carrie, M Elsässer… - The Plant …, 2020 - Wiley Online Library
Mitochondria host vital cellular functions, including oxidative phosphorylation and co‐factor
biosynthesis, which are reflected in their proteome. At the cellular level plant mitochondria …

Getting around the cell: physical transport in the intracellular world

SS Mogre, AI Brown, EF Koslover - Physical Biology, 2020 - iopscience.iop.org
Eukaryotic cells face the challenging task of transporting a variety of particles through the
complex intracellular milieu in order to deliver, distribute, and mix the many components that …

Sphingolipids as a culprit of mitochondrial dysfunction in insulin resistance and type 2 diabetes

K Roszczyc-Owsiejczuk, P Zabielski - Frontiers in endocrinology, 2021 - frontiersin.org
Insulin resistance is defined as a complex pathological condition of abnormal cellular and
metabolic response to insulin. Obesity and consumption of high-fat diet lead to ectopic …

Mitochondria in disease: changes in shapes and dynamics

BC Jenkins, K Neikirk, P Katti, SM Claypool… - Trends in biochemical …, 2024 - cell.com
Mitochondrial structure often determines the function of these highly dynamic,
multifunctional, eukaryotic organelles, which are essential for maintaining cellular health …

Beyond fission and fusion—Diving into the mysteries of mitochondrial shape

N Preminger, M Schuldiner - Plos Biology, 2024 - journals.plos.org
Mitochondrial shape and network formation have been primarily associated with the well-
established processes of fission and fusion. However, recent research has unveiled an …

Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization

S Caballero-Mancebo, R Shinde, M Bolger-Munro… - Nature Physics, 2024 - nature.com
Contraction and flow of the actin cell cortex have emerged as a common principle by which
cells reorganize their cytoplasm and take shape. However, how these cortical flows interact …

The roles of p53 in mitochondrial dynamics and cancer metabolism: the pendulum between survival and death in breast cancer?

DE Moulder, D Hatoum, E Tay, Y Lin, EM McGowan - Cancers, 2018 - mdpi.com
Cancer research has been heavily geared towards genomic events in the development and
progression of cancer. In contrast, metabolic regulation, such as aberrant metabolism in …