Undervalued and novel roles of heterogeneous nuclear ribonucleoproteins in autoimmune diseases: Resurgence as potential biomarkers and targets
K Chen, M Luo, Y Lv, Z Luo… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Autoimmune diseases are mainly characterized by the abnormal autoreactivity due to the
loss of tolerance to specific autoantigens, though multiple pathways associated with the …
loss of tolerance to specific autoantigens, though multiple pathways associated with the …
Exploring precision treatments in immune‐mediated inflammatory diseases: Harnessing the infinite potential of nucleic acid delivery
L Xu, Z Shao, X Fang, Z Xin, S Zhao, H Zhang… - …, 2024 - Wiley Online Library
Immune‐mediated inflammatory diseases (IMIDs) impose an immeasurable burden on
individuals and society. While the conventional use of immunosuppressants and disease …
individuals and society. While the conventional use of immunosuppressants and disease …
[HTML][HTML] The human bone marrow plasma cell compartment in rheumatoid arthritis-Clonal relationships and anti-citrulline autoantibody producing cells
A Hensvold, B Horuluoglu, P Sahlström… - Journal of …, 2023 - Elsevier
A majority of circulating IgG is produced by plasma cells residing in the bone marrow (BM).
Long-lived BM plasma cells constitute our humoral immune memory and are essential for …
Long-lived BM plasma cells constitute our humoral immune memory and are essential for …
Genome-wide analysis of abnormal splicing regulators and alternative splicing involved in immune regulation in systemic lupus erythematosus
B Xu, Y Liu, G Chen, P Jiang, Y Qu, M Wang, X Kao - Autoimmunity, 2025 - Taylor & Francis
Systemic lupus erythematosus (SLE) is an autoimmune disease with complex clinical
manifestations and no current cure. Alternative splicing (AS) plays a key role in SLE by …
manifestations and no current cure. Alternative splicing (AS) plays a key role in SLE by …
Functional analysis of autoantibody signatures in rheumatoid arthritis
L Milchram, A Fischer, J Huber, R Soldo, D Sieghart… - Molecules, 2022 - mdpi.com
For the identification of antigenic protein biomarkers for rheumatoid arthritis (RA), we
conducted IgG profiling on high density protein microarrays. Plasma IgG of 96 human …
conducted IgG profiling on high density protein microarrays. Plasma IgG of 96 human …
Tailored therapeutic decision of rheumatoid arthritis using proteomic strategies: how to start and when to stop?
SF Chen, FC Yeh, CY Chen, HY Chang - Clinical Proteomics, 2023 - Springer
Unpredictable treatment responses have been an obstacle for the successful management
of rheumatoid arthritis. Although numerous serum proteins have been proposed, there is a …
of rheumatoid arthritis. Although numerous serum proteins have been proposed, there is a …
[PDF][PDF] AUF1 modulates apoptosis via regulating transcription and alternative splicing of immune response genes in auditory hair cells
L Li, Z Wang, K Xu, X Bai, W Wu, Z Zhang, X Chen - 2023 - assets-eu.researchsquare.com
Background: AU-rich element RNA-binding factor 1 (AUF1) is a multifunctional RNA binding
proteins (RBPs) in post-transcriptional gene regulation. However, it remains unclear whether …
proteins (RBPs) in post-transcriptional gene regulation. However, it remains unclear whether …
Autoantikörper gegen natives und citrulliniertes hnRNP-DL definieren das" Fenster des Behandlungserfolgs" und identifizieren Risikopersonen für die Entwicklung …
B Marklein - 2023 - refubium.fu-berlin.de
Hintergrund: Autoantikörper gegen das native und citrullinierte heterogene nukleäre
Ribonukleoprotein-D-like (hnRNP-DL; JKTBP) wurden bei Patienten mit systemischem …
Ribonukleoprotein-D-like (hnRNP-DL; JKTBP) wurden bei Patienten mit systemischem …