Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …

Vascular smooth muscle (VSM) cells, endothelial cells (EC), and pericytes that form the
walls of vessels in the microcirculation express a diverse array of ion channels that play an …

Shal-type (Kv4. x) K+ channels are expressed in a variety of tissue, with particularly high
levels in the brain and heart. These channels are the primary subunits that contribute to …

Smooth muscle (SM) is essential to all aspects of human physiology and, therefore, key to
the maintenance of life. Ion channels expressed within SM cells regulate the membrane …

Maintaining the proper balance between cell apoptosis and proliferation is required for
normal tissue homeostasis; when this balance is disrupted, disease such as pulmonary …

This study characterized functional ion channels in cultured undifferentiated human
mesenchymal stem cells (hMSCs) from bone marrow with whole‐cell patch clamp and …

Penile erection is dependent on the nitric oxide (NO)/cGMP‐dependent protein kinase I
(PKGI) pathway. One important target of PKGI in smooth muscle is the large‐conductance …

The large K+ channel functional diversity in the pulmonary vasculature results from the
multitude of genes expressed encoding K+ channels, alternative RNA splicing, the post …

Graphene quantum dots (GQDs) recently gain much attention for its medicinal values in
treating diseases such as neurodegeneration and inflammations. However, owing to the …

A new member of a family of proteins characterized by structural similarity to dipeptidyl
peptidase (DPP) IV known as DPP10 was recently identified and linked to asthma …