Functional characterization of human pluripotent stem cell-derived models of the brain with microelectrode arrays

A Pelkonen, C Pistono, P Klecki, M Gómez-Budia… - Cells, 2021 - mdpi.com
Human pluripotent stem cell (hPSC)-derived neuron cultures have emerged as models of
electrical activity in the human brain. Microelectrode arrays (MEAs) measure changes in the …

A review on microelectrode array fabrication techniques and their applications

A Tanwar, HA Gandhi, D Kushwaha… - Materials Today …, 2022 - Elsevier
Biosensors are an important tool for the detection and quantitative analysis of biomolecules
and chemical compounds. There are a number of biosensors available based on the …

Long-acting therapeutic delivery systems for the treatment of gliomas

S Padmakumar, MM Amiji - Advanced Drug Delivery Reviews, 2023 - Elsevier
Despite the emergence of cutting-edge therapeutic strategies and tremendous progress in
research, a complete cure of glioma remains elusive. The heterogenous nature of tumor …

Biohybrid neural interfaces: improving the biological integration of neural implants

M Boulingre, R Portillo-Lara, RA Green - Chemical Communications, 2023 - pubs.rsc.org
Implantable neural interfaces (NIs) have emerged in the clinic as outstanding tools for the
management of a variety of neurological conditions caused by trauma or disease. However …

Recent advances in sensor-integrated brain-on-a-chip devices for real-time brain monitoring

C Zhao, Z Wang, X Tang, J Qin, Z Jiang - Colloids and Surfaces B …, 2023 - Elsevier
Brain science has remained in the global spotlight as an important field of scientific and
technological discovery. Numerous in vitro and in vivo animal studies have been performed …

Microneedles in advanced microfluidic systems: A systematic review throughout lab and organ-on-a-chip applications

R Maia, V Carvalho, R Lima, G Minas, RO Rodrigues - Pharmaceutics, 2023 - mdpi.com
Microneedles (MNs) have been widely used in biomedical applications for drug delivery and
biomarker detection purposes. Furthermore, MNs can also be used as a stand-alone tool to …

Modern microelectronics and microfluidics on microneedles

Y Han, J Li, T Chen, B Gao, H Wang - Analyst, 2023 - pubs.rsc.org
Possessing the attractive advantages of moderate invasiveness and high compliance, there
is no doubt that microneedles (MNs) have been a gradually rising star in the field of …

[HTML][HTML] Exploring the potential of microfluidics for next-generation drug delivery systems

G Bhattacharjee, N Gohil, M Shukla, S Sharma, I Mani… - OpenNano, 2023 - Elsevier
The platform of microfluidics offers a precise control and manipulation over fluids at a small
scale and therefore has gained much attention in recent times. This topic is currently applied …

Implantable microfluidics: methods and applications

T Luo, L Zheng, D Chen, C Zhang, S Liu, C Jiang, Y Xie… - Analyst, 2023 - pubs.rsc.org
Implantable microfluidics involves integrating microfluidic functionalities into implantable
devices, such as medical implants or bioelectronic devices, revolutionizing healthcare by …

In Vivo Penetrating Microelectrodes for Brain Electrophysiology

A Erofeev, I Antifeev, A Bolshakova, I Bezprozvanny… - Sensors, 2022 - mdpi.com
In recent decades, microelectrodes have been widely used in neuroscience to understand
the mechanisms behind brain functions, as well as the relationship between neural activity …