Advances in diagnostic tools and therapeutic approaches for gliomas: A comprehensive review

G Thenuwara, J Curtin, F Tian - Sensors, 2023 - mdpi.com
Gliomas, a prevalent category of primary malignant brain tumors, pose formidable clinical
challenges due to their invasive nature and limited treatment options. The current …

Emerging extracellular vesicle-based carriers for glioblastoma diagnosis and therapy

J Wang, Y Liu, F Liu, S Gan, S Roy, I Hasan, B Zhang… - Nanoscale, 2023 - pubs.rsc.org
Glioblastoma (GBM) treatment is still a big clinical challenge because of its highly malignant,
invasive, and lethal characteristics. After treatment with the conventional therapeutic …

Nuclear Medicine and Cancer Theragnostics: Basic Concepts

V Zoi, M Giannakopoulou, GA Alexiou, P Bouziotis… - Diagnostics, 2023 - mdpi.com
Cancer theragnostics is a novel approach that combines diagnostic imaging and
radionuclide therapy. It is based on the use of a pair of radiopharmaceuticals, one optimized …

Regulation of extracellular vesicle-mediated immune responses against antigen-specific presentation

Y Matsuzaka, R Yashiro - Vaccines, 2022 - mdpi.com
Extracellular vesicles (EVs) produced by various immune cells, including B and T cells,
macrophages, dendritic cells (DCs), natural killer (NK) cells, and mast cells, mediate …

Hsp70 and Calcitonin Receptor Protein in Extracellular Vesicles from Glioblastoma Multiforme: Biomarkers with Putative Roles in Carcinogenesis and Potential for …

G Alberti, CM Sánchez-López, A Marcilla… - International Journal of …, 2024 - mdpi.com
Glioblastoma multiforme (GBM) is a malignancy of bad prognosis, and advances in early
detection and treatment are needed. GBM is heterogenous, with varieties differing in …

Challenges and Promise for Glioblastoma Treatment through Extracellular Vesicle Inquiry

GL Liguori - Cells, 2024 - mdpi.com
Glioblastoma (GB) is a rare but extremely aggressive brain tumor that significantly impacts
patient outcomes, affecting both duration and quality of life. The protocol established by …

The Spectrum of Molecular Pathways in Gliomas—An Up-to-Date Review

R Nafe, E Hattingen - Biomedicines, 2023 - mdpi.com
During the last 20 years, molecular alterations have gained increasing significance in the
diagnosis and biological assessment of tumors. Gliomas represent the largest group of …

Recent Advances in Biomimetic Strategies for the Immunotherapy of Glioblastoma

H You, S Geng, S Li, M Imani, D Brambilla, T Sun… - Biomaterials, 2024 - Elsevier
Immunotherapy is regarded as one of the most promising approaches for treating tumors,
with a multitude of immunotherapeutic thoughts currently under consideration for the lethal …

[PDF][PDF] Extracellular vesicles as modulators of glioblastoma progression and tumor microenvironment

J Dai, Y Jiang, H Hu, S Zhang… - Pathology and Oncology …, 2024 - por-journal.com
Gliomas are common central nervous system (CNS) tumors that are classified according to
morphology and molecular characteristics, graded according to malignancy. The World …

Biosensor-Enhanced Organ-on-a-Chip Models for Investigating Glioblastoma Tumor Microenvironment Dynamics

G Thenuwara, B Javed, B Singh, F Tian - Sensors, 2024 - mdpi.com
Glioblastoma, an aggressive primary brain tumor, poses a significant challenge owing to its
dynamic and intricate tumor microenvironment. This review investigates the innovative …