The extracellular matrix is a critical component of microbial biofilms, such as dental plaque,
maintaining the spatial arrangement of cells and coordinating cellular functions throughout …

Biofilms are microbial communities embedded within an extracellular matrix, forming a
highly organized structure that causes many human infections. Dental caries (tooth decay) is …

As a major etiological agent of human dental caries, Streptococcus mutans resides primarily
in biofilms that form on the tooth surfaces, also known as dental plaque. In addition to caries …

The human microbiota is the community of microorganisms that live upon or within their
human host. The microbiota consists of various microorganisms including bacteria, fungi …

Amyloid fibrils are best known as a product of human and animal protein misfolding
disorders, where amyloid formation is associated with cytotoxicity and disease. It is now …

Alzheimer's disease (AD) is a progressive neurodegenerative pathology affecting milions of
people worldwide associated with deposition of senile plaques. While the genetic and …

In the past two decades, amyloids, typically associated with human diseases, have been
described to play various functional roles in nearly all life forms. The structural and functional …

Biofilms are ubiquitous in the natural and man-made environment. They are defined as
microbes that are encapsulated in an extracellular, self-produced, biofilm matrix. Growing …

Streptococcus mutans is a key cariogenic bacterium responsible for the initiation of tooth
decay. Biofilm formation is a crucial virulence property. We discovered a putative …

Understanding the structure, functionalities and biology of functional amyloids is an issue of
emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria …