Review of recent advances in peripheral nerve stimulation (PNS)

K Chakravarthy, A Nava, PJ Christo… - Current pain and headache …, 2016 - Springer
Peripheral nerve stimulation (PNS) for the treatment of chronic pain has become an
increasingly important field in the arena of neuromodulation, given the ongoing advances in …

[HTML][HTML] Peripheral neuromodulation for the management of headache

I Urits, R Schwartz, D Smoots, L Koop… - … and pain medicine, 2020 - ncbi.nlm.nih.gov
Results The first noninvasive neurostimulator device approved for migraine treatment was
the Cefaly device, an external trigeminal nerve stimulation device (e-TNS) that …

Neurostimulation for intractable chronic pain

TR Deer, S Jain, C Hunter, K Chakravarthy - Brain sciences, 2019 - mdpi.com
The field of neuromodulation has seen unprecedented growth over the course of the last
decade with novel waveforms, hardware advancements, and novel chronic pain indications …

TLR2 mediates microglial activation and contributes to central sensitization in a recurrent nitroglycerin-induced chronic migraine model

X Liu, W Yang, C Zhu, S Sun, B Yang, S Wu… - Molecular …, 2024 - Springer
Central sensitization is an important pathophysiological mechanism underlying chronic
migraine (CM). Previous studies have shown that microglial activation and subsequent …

Modulation of mechanosensory vibrissal responses in the trigeminocervical complex by stimulation of the greater occipital nerve in a rat model of trigeminal …

N García-Magro, P Negredo, YB Martin… - The journal of headache …, 2020 - Springer
Background Stimulation of the occipital or trigeminal nerves has been successfully used to
treat chronic refractory neurovascular headaches such as migraine or cluster headache, and …

The greater occipital nerve and its spinal and brainstem afferent projections: A stereological and tract‐tracing study in the rat

N García‐Magro, YB Martin, P Negredo… - Journal of …, 2018 - Wiley Online Library
The neuromodulation of the greater occipital nerve (GON) has proved effective to treat
chronic refractory neurovascular headaches, in particular migraine and cluster headache …

Occipital nerve stimulation in chronic migraine: the relationship between perceived sensory quality, perceived sensory location, and clinical efficacy—a prospective …

CH Göbel, A Göbel, U Niederberger, A Heinze… - Pain and Therapy, 2020 - Springer
Introduction Occipital nerve stimulation (ONS) is used to treat therapy-resistant chronic
migraine. Clinical use has resulted in a wide intraindividual and interindividual variation of …

Occipital nerve stimulation attenuates neuronal firing response to mechanical stimuli in the ventral posteromedial thalamus of a rodent model of chronic migraine

I Walling, H Smith, LE Gee, B Kaszuba… - …, 2017 - journals.lww.com
BACKGROUND Chronic migraine (CM) is a highly debilitating disease, and many patients
remain refractory to medicinal therapy. Given the convergent nature of neuronal networks in …

[HTML][HTML] Evaluation of the efficacy of therapeutic ultrasound in the treatment of migraine

BM Ökmen, A Güneş, L Altan - Turkish Journal of Physical …, 2022 - ncbi.nlm.nih.gov
Evaluation of the efficacy of therapeutic ultrasound in the treatment of migraine - PMC Back to
Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage …

The use of focused ultrasound for the treatment of cutaneous allodynia associated with chronic migraine

I Walling, D Panse, L Gee, T Maietta, B Kaszuba… - Brain Research, 2018 - Elsevier
Chronic migraines (CM) are the third most common disease and are refractory to medical
treatment in 15% of patients. Currently, temporary relief is achieved with steroid blocks or …