Advances in synthetic biology and artificial intelligence (AI) have provided new opportunities
for modern biotechnology. High-performance cell factories, the backbone of industrial …

Sphingolipids (SLs) are essential to fungal survival and represent a major class of structural
and signaling lipids. Unique SL structures and their biosynthetic enzymes in filamentous …

The remarkable metabolic diversity observed in nature has provided a foundation for
sustainable production of a wide array of valuable molecules. However, transferring the …

Large-scale kinetic models provide the computational means to dynamically link metabolic
reaction fluxes to metabolite concentrations and enzyme levels while also conforming to …

Kinetic modeling of in vitro enzymatic reaction networks is vital to understand and control the
complex behaviors emerging from the nonlinear interactions inside. However, modeling is …

Chinese sausage is a highly valued traditional meat product in China, renowned for its
distinctive flavor and characteristic red color (Xiao, Liu, Chen, Xie, & Li, 2020). Typically …

ABSTRACT SCS7 is a fatty acid 2-hydroxylase required for the synthesis of inositol
phosphorylceramide but is not essential for normal growth in Saccharomyces cerevisiae …

Production of value-added, plant-derived compounds in microbes increasingly attracts
commercially interest in food and pharmaceutical industries. However, plant metabolic …

Results Overview of the nucleotide salvage pathway The in vitro ERN constructed in this
work derives from the nucleotide salvage pathway (Fig. 1 a), which regenerates nucleotides …

Biology, from the ancient Greek,“study of life”, is the most fascinating yet complex of all
sciences. Its understanding is paramount in solving many current problems we face in our …