Galectins is a family of non-classically secreted, β-galactoside-binding proteins that has
recently received considerable attention in the spatio-temporal regulation of surface 'signal …

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic
outcomes, independent of overall adiposity. To increase our understanding of the genetic …

Sex-determining region Y-related high-mobility-group box transcription factor 11 (SOX11) is
an essential member of the SOX transcription factors and has been highlighted as an …

Background Cases of mantle cell lymphoma with indolent behavior have been reported, but
are poorly identified by current clinical risk models. Early studies found peripheral blood …

Mantle cell lymphoma (MCL) is an aggressive B cell lymphoma, where survival has been
remarkably improved by use of protocols including high dose cytarabine, rituximab and …

Abstract Background: Bladder cancer (BCa) remains a lethal malignancy that can be cured if
detected early. DNA hypermethylation is a common epigenetic abnormality in cancer that …

Basal-like breast cancers (BLBCs) are aggressive breast cancers associated with poor
survival. Defining the key drivers of BLBC growth will allow identification of molecules for …

SOX11 is a relevant element in the pathogenesis of MCL and has been instrumental to
identify two distinct clinicobiological subtypes of this tumor. Further studies should clarify the …

The present study was performed to clarify the significance of DNA methylation alterations
during endometrial carcinogenesis. Genome-wide DNA methylation analysis and targeted …

SOX11 expression has been recently shown to be useful in the diagnosis of mantle cell
lymphoma (MCL), including cyclin D1-negative MCL with typical morphology. We evaluated …