Neuropeptides play important modulatory roles throughout the nervous system, functioning
as direct effectors or as interacting partners with other neuropeptide and neurotransmitter …

Corticotropin-releasing factor (CRF) is a 41-amino acid neuropeptide that is involved in
stress-related physiology and behavior, including control of the hypothalamic-pituitary …

Serotonin neurons play a major role in many normal and pathological brain functions. In the
rat these neurons have a varying number of cotransmitters, including neuropeptides. Here …

Corticotropin-releasing factor (CRF) has a key role in the central stress response, and
altered levels of this neuropeptide are linked to stress-related psychopathologies such as …

Hypersecretion of central corticotropin-releasing hormone (CRH) has been implicated in the
pathophysiology of affective disorders. Both, basic and clinical studies suggested that …

The present study examined the effect of prenatal stress in rats from days 13–20 of gestation
on anxiogenic behaviour in the elevated plus maze (EPM) together with changes in the …

Corticotropin releasing factor (CRH) has been shown to contribute critically to molecular and
neuroendocrine responses to stress during both adulthood and development. This peptide …

Neuropathic pain is strongly associated with mood disorders like anxiety and depression.
Corticotropin‐releasing factor (CRF) plays a prominent role in these disorders as it is up …

Visceral hypersensitivity has been implicated as an important pathophysiological
mechanism in functional gastrointestinal disorders. In this study, we investigated whether the …

Introduction Physical activity is recommended as an alternative treatment for depression.
Myokines, which are secreted from skeletal muscles during physical activity, play an …