Defining dry eye from a clinical perspective

K Tsubota, SC Pflugfelder, Z Liu, C Baudouin… - International journal of …, 2020 - mdpi.com
Over the past decades, the number of patients with dry eye disease (DED) has increased
dramatically. The incidence of DED is higher in Asia than in Europe and North America …

TFOS DEWS II diagnostic methodology report

JS Wolffsohn, R Arita, R Chalmers, A Djalilian… - The ocular …, 2017 - Elsevier
The role of the Tear Film and Ocular Surface Society (TFOS) Dry Eye Workshop (DEWS) II
Diagnostic Methodology Subcommittee was 1) to identify tests used to diagnose and monitor …

Biological functions of tear film

SC Pflugfelder, ME Stern - Experimental eye research, 2020 - Elsevier
Tears have a vital function to protect and lubricate the ocular surface. Tear production,
distribution and clearance is tightly regulated by the lacrimal functional unit (LFU) to meet …

[HTML][HTML] Measuring contrast sensitivity

DG Pelli, P Bex - Vision research, 2013 - Elsevier
Contrast sensitivity defines the threshold between the visible and invisible, which has
obvious significance for basic and clinical vision science. Fechner's 1860 review reported …

Dry eye disease: impact on quality of life and vision

M Uchino, DA Schaumberg - Current ophthalmology reports, 2013 - Springer
Dry eye disease (DED) is a growing public health concern causing ocular discomfort,
fatigue, and visual disturbance that interferes with quality of life (QoL), including aspects of …

Impact of dry eye syndrome on vision-related quality of life

B Miljanović, R Dana, DA Sullivan… - American journal of …, 2007 - Elsevier
PURPOSE: To evaluate the impact of dry eye syndrome (DES) on vision-associated quality
of life. DESIGN: Cross-sectional study. METHODS: We identified 450 participants in the …

Modern approach to the treatment of dry eye, a complex multifactorial disease: a PICASSO board review

P Aragona, G Giannaccare, R Mencucci… - British Journal of …, 2021 - bjo.bmj.com
Dry eye disease (DED) is a growing public health concern affecting quality of life and visual
function, with a significant socio-economic impact. It is characterised by the loss of …

Rethinking dry eye disease: a perspective on clinical implications

AJ Bron, A Tomlinson, GN Foulks, JS Pepose… - The ocular …, 2014 - Elsevier
Publication of the DEWS report in 2007 established the state of the science of dry eye
disease (DED). Since that time, new evidence suggests that a rethinking of traditional …

The international workshop on meibomian gland dysfunction: report of the subcommittee on tear film lipids and lipid–protein interactions in health and disease

KB Green-Church, I Butovich, M Willcox… - … & visual science, 2011 - iovs.arvojournals.org
Understanding the molecular composition (eg, proteins and lipids) of the tear film (TF) and
the contribution of the meibomian gland to the TF is critical in gaining knowledge about TF …

The ocular surface and tear film and their dysfunction in dry eye disease

M Rolando, M Zierhut - Survey of ophthalmology, 2001 - Elsevier
The ocular surface, tear film, lacrimal glands, and eyelids act as a functional unit to preserve
the quality of the refractive surface of the eye and to resist injury and protect the eye against …