A critical review of effect modeling for ecological risk assessment of plant protection products

F Larras, S Charles, A Chaumot, C Pelosi… - … Science and Pollution …, 2022 - Springer
A wide diversity of plant protection products (PPP) is used for crop protection leading to the
contamination of soil, water, and air, which can have ecotoxicological impacts on living …

Approaching a closer surrogate for the biologically effective dose with subcellular partitioning-based toxicokinetic models

TTY Le, O Geffard, A Geffard… - Critical Reviews in …, 2023 - Taylor & Francis
A general concept in risk assessment is that a threshold of exposure exists above which
adverse effects are initiated. Toxicity is related to the target-site concentration or the …

Fish Physiologically Based Toxicokinetic Modeling Approach for In Vitro–In Vivo and Cross-Species Extrapolation of Endocrine-Disrupting Chemicals in Risk …

R Xie, Y Xu, M Ma, Z Wang - Environmental Science & Technology, 2024 - ACS Publications
High-throughput in vitro assays combined with in vitro–in vivo extrapolation (IVIVE) leverage
in vitro responses to predict the corresponding in vivo exposures and thresholds of concern …

Influence of the exposure concentration of dissolved cadmium on its organotropism, toxicokinetic and fate in Gammarus fossarum

O Gestin, T Lacoue-Labarthe, N Delorme… - Environment …, 2023 - Elsevier
Abstract Information on the relationship between the exposure concentrations of metals and
their biodistribution among organs remained scarce in invertebrates. The objective of this …

Tracking Nano-and Microplastics Accumulation and Egestion in a Marine Copepod by Novel Fluorescent AIEgens: Kinetic Modeling of the Rhythm Behavior

Z Dong, WX Wang - Environmental Science & Technology, 2023 - ACS Publications
Nano-and microplastics (NMPs) are now prevalent in the marine environment. This study
quantified the uptake and depuration kinetics of spherical polystyrene NMPs of different …

Organ-specific accumulation of cadmium and zinc in Gammarus fossarum exposed to environmentally relevant metal concentrations

O Gestin, C Lopes, N Delorme, L Garnero… - Environmental …, 2022 - Elsevier
One of the best approaches for improving the assessment of metal toxicity in aquatic
organisms is to study their organotropism (ie, the distribution of metals among organs) …

In Vivo Mercury (De)Methylation Metabolism in Cephalopods under Different pCO2 Scenarios

S Gentès, A Minet, C Lopes, E Tessier… - Environmental …, 2023 - ACS Publications
This work quantified the accumulation efficiencies of Hg in cuttlefish, depending on both
organic (MeHg) and inorganic (Hg (II)) forms, under increased p CO2 (1600 μatm). Cuttlefish …

[HTML][HTML] Identification and organ-specific patterns of expression of two metallothioneins in the sentinel species Gammarus fossarum

D Degli Esposti, A Lalouette, K Gaget, L Lepeule… - … and Physiology Part B …, 2024 - Elsevier
Metal pollution is a major concern for aquatic environments. Widespread contamination by
various trace metal ions has been described in freshwater streams as well as their …

Multiple reaction monitoring mass spectrometry for the discovery of environmentally modulated proteins in an aquatic invertebrate sentinel species, Gammarus …

M Leprêtre, O Geffard, A Espeyte, J Faugere… - Environmental …, 2022 - Elsevier
Multiple reaction monitoring (MRM) mass spectrometry is emerging as a relevant tool for
measuring customized molecular markers in freshwater sentinel species. While this …

In silico methods for environmental risk assessment: Principles, tiered approaches, applications, and future perspectives

MC Astuto, MR Di Nicola, JV Tarazona… - In Silico methods for …, 2022 - Springer
This chapter aims to introduce the reader to the basic principles of environmental risk
assessment of chemicals and highlights the usefulness of tiered approaches within weight of …