RNA functions by interacting with its intended targets structurally. However, due to the
dynamic nature of RNA molecules, RNA structures are difficult to determine experimentally …

The exponential growth of big data in RNA biology (RB) has led to the development of deep
learning (DL) models that have driven crucial discoveries. As constantly evidenced by DL …

Compact, lightweight, and on-chip spectrometers are required to develop portable and
handheld sensing and analysis applications. However, the performance of these …

Huntington's disease (HD) is a dominant neurological disorder caused by an expanded HTT
exon 1 CAG repeat that lengthens huntingtin's polyglutamine tract. Lowering mutant …

Drug-eluting stent implantation suppresses the excessive proliferation of smooth muscle
cells to reduce in-stent restenosis. However, the efficacy of drug-eluting stents remains …

At the initial stage of drug discovery, identifying novel targets with maximal efficacy and
minimal side effects can improve the success rate and portfolio value of drug discovery …

The data explosion driven by advancements in genomic research, such as high-throughput
sequencing techniques, is constantly challenging conventional methods used in genomics …

Familial dysautonomia (FD) is a currently untreatable, neurodegenerative disease caused
by a splicing mutation (c. 2204+ 6T> C) that causes skipping of exon 20 of the elongator …

Familial dysautonomia (FD) is a rare neurodegenerative disease caused by a splicing
mutation in elongator acetyltransferase complex subunit 1 (ELP1). This mutation leads to the …

Due to the low number of patients, rare genetic diseases are a special challenge for the
development of therapies, especially for diseases that result from numerous, patient‐specific …