Amphiphilic block copolymers are widely utilized in the design of formulations owing to their
unique physicochemical properties, flexible structures and functional chemistry. Amphiphilic …

Abstract Matrix metalloproteinase-9 (MMP-9) plays major roles in extracellular matrix (ECM)
remodeling and membrane protein cleavage, suggesting a high correlation with cancer cell …

Due to their N-substitution, peptoids are generally regarded as resistant to biological
degradation, such as enzymatic and hydrolytic mechanisms. This stability is an especially …

Key hallmarks of inflammation include proinflammatory (M1) macrophages and production
of reactive oxygen species (ROS). Therefore, we developed a ROS-sensitive, photoacoustic …

Proteases, especially MMPs, are attractive biomarkers given their central role in both
physiological and pathological processes. Distinguishing MMP activity with degradable …

Identifying pro-inflammatory macrophages (M1) is of immense importance to diagnose,
monitor, and treat various pathologies. In addition, adoptive cell therapies, where harvested …

The utility of active proteases as biomarkers is often limited by overlapping substrate
specificity. Here, this feature is leveraged to develop a quantitative pattern-recognition …

Despite significant advances in radiotherapy (RT) treatment modalities, highly radioresistant
forms of cancer such as Glioblastoma Multiforme (GBM) remains a major clinical challenge …

Abstract Development of multi-functional materials and biosensors that can achieve an in-
situ response designed by the user is a current need in the biomaterials field, especially in …