B cells play a fundamental role in host defenses against viral infections. Profiling the B cell
response elicited by SARS-CoV-2 vaccination, including the generation and persistence of …

Single-cell T cell and B cell antigen receptor-sequencing data analysis can potentially
perform in-depth assessments of adaptive immune cells that inform on understanding …

Understanding persistence and evolution of B cell clones after COVID-19 infection and
vaccination is crucial for predicting responses against emerging viral variants and optimizing …

Dynamic changes of the paired heavy and light chain B cell receptor (BCR) repertoire
provide an essential insight into understanding the humoral immune response post-SARS …

Broadly neutralizing antibodies (bNAbs), when administered through passive immunization,
are protective against HIV-1 infection. Current HIV-1 vaccine strategies are aimed at guiding …

Introduction The success of the human body in fighting SARS-CoV2 infection relies on
lymphocytes and their antigen receptors. Identifying and characterizing clinically relevant …

Adaptive Immune Receptor Repertoire sequencing (AIRR-seq) is a valuable experimental
tool to study the immune state in health and following immune challenges such as infectious …

Single-cell RNA sequencing (scRNA-seq) can resolve transcriptional features from
individual cells, but scRNA-seq techniques capable of resolving the variable regions of B …

Background & Aims Liver injury after COVID-19 vaccination is very rare and shows clinical
and histomorphological similarities with autoimmune hepatitis (AIH). Little is known about …

While our understanding of SARS-CoV-2 pathogenesis and antibody responses following
infection and vaccination has improved tremendously since the outbreak in 2019, the …