[HTML][HTML] Subacute ruminal acidosis in dairy herds: Microbiological and nutritional causes, consequences, and prevention strategies

ME Elmhadi, DK Ali, MK Khogali, H Wang - Animal Nutrition, 2022 - Elsevier
Dairy cattle are frequently fed high-concentrate (HC) diets in modern intensive feeding
systems, especially in the transition period. During this period, cows face many alterations …

Real-time monitoring of ruminal microbiota reveals their roles in dairy goats during subacute ruminal acidosis

X Chen, X Su, J Li, Y Yang, P Wang, F Yan… - npj Biofilms and …, 2021 - nature.com
Ruminal microbiota changes frequently with high grain diets and the occurrence of subacute
ruminal acidosis (SARA). A grain-induced goat model of SARA, with durations of a …

Potential protective effects of thiamine supplementation on the ruminal epithelium damage during subacute ruminal acidosis

J Ma, AM Shah, Z Wang, X Fan - Animal Science Journal, 2021 - Wiley Online Library
In ruminants, the ruminal epithelium not only has the function of absorbing nutrients but also
is an important tissue to prevent harmful substances in the rumen from entering the blood …

Pentoxifylline and thiamine ameliorate rhabdomyolysis-induced acute kidney injury in rats via suppressing TLR4/NF-κB and NLRP-3/caspase-1/gasdermin mediated …

L Al-Kharashi, H Attia, A Alsaffi, T Almasri… - Toxicology and Applied …, 2023 - Elsevier
Acute kidney injury (AKI) is a common complication of rhabdomyolysis (RM), a syndrome
characterized by skeletal muscle damage resulting in renal tubular oxidative stress …

Thiamine alleviates high-concentrate-diet-induced oxidative stress, apoptosis, and protects the rumen epithelial barrier function in goats

Y Ma, Y Zhang, M Elmhadi, H Zhang… - Frontiers in Veterinary …, 2021 - frontiersin.org
High-concentrate diets are continually used in ruminants to meet the needs of milk yield,
which can lead to the occurrence of subacute rumen acidosis in ruminants. This study …

Thiamine supplementation alleviates lipopolysaccharide-triggered adaptive inflammatory response and modulates energy state via suppression of NFκB/P38 MAPK …

Y Ma, M Elmhadi, C Wang, Z Li, H Zhang, B He, X Zhao… - Antioxidants, 2022 - mdpi.com
Studies have shown that exogenous thiamine (THI) supplementation can alleviate
inflammation and promote rumen epithelial development in goats and cows. This research …

Strontium attenuates LPS-induced inflammation via TLR4/MyD88/NF-κB pathway in bovine ruminal epithelial cells

P Tan, J Yang, F Yi, L Mei, Y Wang, C Zhao… - … Trace Element Research, 2024 - Springer
Subacute ruminal acidosis (SARA) is a common nutritional metabolic disease in ruminants
that causes significant economic losses to dairy farming. Strontium (Sr) is known to be …

Illumina sequencing and metabolomics analysis reveal thiamine modulation of ruminal microbiota and metabolome characteristics in goats fed a high-concentrate diet

Y Ma, C Wang, H Zhang, L Yu, L Dong… - Frontiers in …, 2021 - frontiersin.org
Long-term supplementation of a high-concentrate diet enhances the accumulation of lactate
and decrease in pH in goat rumen, thereby disrupting the composition of microbial …

[HTML][HTML] Thiamine ameliorates metabolic disorders induced by a long-term high-concentrate diet and promotes rumen epithelial development in goats

Y Ma, C Wang, M Elmhadi, H Zhang, Y Han… - Journal of Dairy …, 2021 - Elsevier
Data indicate that dietary thiamine supplementation can partly alleviate rumen epithelium
inflammation and barrier function in goats fed a high-concentrate diet. The current work …

[HTML][HTML] Variability in chewing, ruminal fermentation, digestibility and bacterial communities between subacute ruminal acidosis-susceptible and acidosis-tolerant …

ZA Zhang, F Li, ZY Ma, FD Li, ZL Wang, SR Li… - animal, 2023 - Elsevier
Sorting behaviour is a common phenomenon observed in ruminants when they are provided
with a total mixed ration, which contributes to variations in the severity of subacute ruminal …