Emerging role of MiR-192-5p in human diseases

F Ren, Y Yao, X Cai, G Fang - Frontiers in Pharmacology, 2021 - frontiersin.org
MicroRNAs (miRNAs) are a type of small non-coding RNAs that play an essential role in
numerous biological processes by regulating the post-transcriptional expression of target …

The regulatory role of microRNA in hepatitis-B virus-associated hepatocellular carcinoma (HBV-HCC) pathogenesis

K Sartorius, J Makarova, B Sartorius, P An, C Winkler… - Cells, 2019 - mdpi.com
The incidence and mortality of hepatitis B virus (HBV)-associated hepatocellular carcinoma
(HBV-HCC) is an intractable public health problem in developing countries that is …

The microRNA‐99 family modulates hepatitis B virus replication by promoting IGF‐1R/PI3K/Akt/mTOR/ULK1 signaling‐induced autophagy

Y Lin, W Deng, J Pang, T Kemper, J Hu… - Cellular …, 2017 - Wiley Online Library
MicroRNAs are small highly conserved noncoding RNAs that are widely expressed in
multicellular organisms and participate in the regulation of various cellular processes …

[HTML][HTML] miR-192-5p regulates lipid synthesis in non-alcoholic fatty liver disease through SCD-1

XL Liu, HX Cao, BC Wang, FZ Xin… - World journal of …, 2017 - ncbi.nlm.nih.gov
AIM To evaluate the levels of miR-192-5p in non-alcoholic fatty liver disease (NAFLD)
models and demonstrate the role of miR-192-5p in lipid accumulation. METHODS Thirty …

Human hepatocyte-enriched miRNA-192-3p promotes HBV replication through inhibiting Akt/mTOR signalling by targeting ZNF143 in hepatic cell lines

F Li, Y Deng, S Zhang, B Zhu, J Wang… - Emerging microbes & …, 2022 - Taylor & Francis
Previous studies have revealed multiple tissue-or cell-specific or enriched miRNA profiles.
However, miRNA profiles enriched in hepatic cell types and their effect on HBV replication …

Liver damage and microRNAs: An update

E Cione, DM Abrego Guandique, MC Caroleo… - Current Issues in …, 2022 - mdpi.com
One of the major organs in the body with multiple functions is the liver. It plays a central role
in the transformation of macronutrients and clearance of chemicals and drugs. The serum …

Circulating liver-specific microRNAs as noninvasive diagnostic biomarkers of hepatic diseases in human

G Musaddaq, N Shahzad, MA Ashraf, MI Arshad - Biomarkers, 2019 - Taylor & Francis
Context: Hepatitis is an endemic disease worldwide leading to chronic and debilitating
cancers. The viral agents and hepatotoxic substances lead to damage of hepatocytes and …

[HTML][HTML] Circulating microRNAs as non-invasive biomarkers for hepatitis B virus liver fibrosis

DG Iacob, A Rosca, SM Ruta - World journal of gastroenterology, 2020 - ncbi.nlm.nih.gov
Viruses can alter the expression of host microRNAs (MiRNA s) and modulate the immune
response during a persistent infection. The dysregulation of host MiRNA s by hepatitis B …

Plasma microRNA levels are associated with hepatitis B e antigen status and treatment response in chronic hepatitis B patients

MH Van Der Ree, L Jansen, Z Kruize… - The Journal of …, 2017 - academic.oup.com
Abstract Background. Hepatitis B virus (HBV) modulates microRNA (miRNA) expression to
support viral replication. The aim of this study was to identify miRNAs associated with …

Serum microRNA profiles and pathways in hepatitis B-Associated hepatocellular carcinoma: a South African study

K Sartorius, B Sartorius, C Winkler… - International Journal of …, 2024 - mdpi.com
The incidence and mortality of hepatocellular carcinoma (HCC) in Sub-Saharan Africa is
projected to increase sharply by 2040 against a backdrop of limited diagnostic and …