Cancer is a complex disease involving alterations of multiple processes, with both genetic
and epigenetic features contributing as core factors to the disease. In recent years, it has …

Epigenetics refers to the DNA chemistry changes that result in the modification of gene
transcription and translation independently of the underlying DNA coding sequence …

Breast cancer is the most prevalent cancer in the world. Currently, the main treatments for
breast cancer are radiotherapy, chemotherapy, targeted therapy and surgery. The treatment …

miRNAs are some of the most well-characterized regulators of gene expression. Integral to
several physiological processes, their aberrant expression often drives the pathogenesis of …

Breast cancer, as a highly heterogeneous malignant tumor, is one of the primary causes of
death among females worldwide. The etiology of breast cancer involves aberrant epigenetic …

MicroRNAs (miRNAs) are noncoding single‐stranded RNAs, approximately 20‐24
nucleotides in length, known as powerful posttranscriptional regulators. miRNAs play …

Disruption in DNA methylation processes can lead to alteration in gene expression and
function that would ultimately result in malignant transformation. In this way, studies have …

Human cancers are heterogenous by their cell composition and origination site. Cancer
metastasis generates the conundrum of the unknown origin of migrated tumor cells. Tracing …

MicroRNAs (miRNAs) have been found to play an important role in breast cancer,
functioning either as potential oncogenes or tumor suppressor genes, but their role in the …

Fertility preservation is an important issue in breast cancer patients undergoing oncological
treatment. Fertility counseling is a crucial need given the physical and psychological stress …