M Jeong, Y Lee, J Park, H Jung, H Lee - Advanced drug delivery reviews, 2023 - Elsevier
RNA therapeutics show a significant breakthrough for the treatment of otherwise incurable diseases and genetic disorders by regulating disease-related gene expression. The …
The advent of genome editing has transformed the therapeutic landscape for several debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
The development of nanoparticle-based drug formulations has yielded the opportunities to address and treat challenging diseases. Nanoparticles vary in size but are generally ranging …
J Ding, J Chen, L Gao, Z Jiang, Y Zhang, M Li, Q Xiao… - Nano Today, 2019 - Elsevier
Nanomedicine has been extensively explored to enhance the efficacy of chemotherapy with modest therapeutic efficacy in the clinic, owing to various factors. A primary factor is …
SY Li, H Cheng, BR Xie, WX Qiu, JY Zeng, CX Li… - ACS …, 2017 - ACS Publications
Selectively cuting off the nutrient supply and the metabolism pathways of cancer cells would be a promising approach to improve the efficiency of cancer treatment. Here, a cancer …
Q Sun, Z Zhou, N Qiu, Y Shen - Advanced materials, 2017 - Wiley Online Library
Current cancer nanomedicines can only mitigate adverse effects but fail to enhance therapeutic efficacies of anticancer drugs. Rational design of next‐generation cancer …
Over the years, a plethora of materials–natural and synthetic–have been engineered at a nanoscopic level and explored for drug delivery. Nanocarriers based on such materials …
mRNA vaccines elicit a potent immune response including antibodies and cytotoxic T cells. mRNA vaccines are currently evaluated in clinical trials for cancer immunotherapy …
X Jing, H Hu, Y Sun, B Yu, H Cong, Y Shen - Small Methods, 2022 - Wiley Online Library
The tumor microenvironment (TME), including intracellular and extracellular microenvironment, contains many biochemical indicators (such as acidity/alkalinity, oxygen …