A field guide to foldamers

DJ Hill, MJ Mio, RB Prince, TS Hughes… - Chemical …, 2001 - ACS Publications
The breadth of structure and function displayed by the molecules of biology is remarkable.
Considering that there are only three major biopolymer backbones (proteins, ribonucleic …

Synthetic helical polymers: conformation and function

T Nakano, Y Okamoto - Chemical Reviews, 2001 - ACS Publications
The high functionalities of naturally occurring macromolecules such as proteins and genes
arise from their precisely ordered stereostructures. 1 In such systems, the helix is often found …

Self‐assembling organic nanotubes

DT Bong, TD Clark, JR Granja… - Angewandte Chemie …, 2001 - Wiley Online Library
Hollow tubular structures of molecular dimensions perform diverse biological functions in
nature. Examples include scaffolding and packaging roles played by cytoskeletal …

Chiral architectures from macromolecular building blocks

JJLM Cornelissen, AE Rowan, RJM Nolte… - Chemical …, 2001 - ACS Publications
In the course of evolution, Nature has developed a multitude of biomacromolecules tailored
to deal with complicated tasks such as information storage, support of tissue, transport, and …

Foldamer-based molecular recognition

RB Prince, SA Barnes, JS Moore - Journal of the American …, 2000 - ACS Publications
The ordered solution conformation of a synthetic chain molecule has been used to create a
high-affinity binding site for small-molecule guests. The diastereoselective complexation of …

Formation of supramolecular channels by reversible unwinding-rewinding of bis (indole) double helix via ion coordination

D Mondal, M Ahmad, B Dey, A Mondal… - Nature …, 2022 - nature.com
Stimulus-responsive reversible transformation between two structural conformers is an
essential process in many biological systems. An example of such a process is the …

Helicity inversion in responsive foldamers induced by achiral halide ion guests

RM Meudtner, S Hecht - Angewandte Chemie International …, 2008 - Wiley Online Library
Interest in foldamers [1] and helically folding polymers [2] has increased considerably over
the past decade, reflecting the vast potential of this emerging field.[3] One particularly …

Shell crosslinked polymer assemblies: nanoscale constructs inspired from biological systems

KL Wooley - Journal of Polymer Science Part A: Polymer …, 2000 - Wiley Online Library
The general approach involving the organization of polymers into micellar assemblies
followed by stabilization through covalent intramicellar crosslinking of the assemblies has …

Synthesis and Structural Characterization of Helix-Forming β-Peptides:  trans-2-Aminocyclopentanecarboxylic Acid Oligomers

DH Appella, LA Christianson, DA Klein… - Journal of the …, 1999 - ACS Publications
Synthetic protocols and circular dichroism (CD) spectra are reported for a series of
oligomers of (R, R)-trans-2-aminocyclopentanecarboxylic acid (trans-ACPC). The two …

Aryl-Substituted C3-Bridged Oligopyrroles as Anion Receptors for Formation of Supramolecular Organogels

H Maeda, Y Haketa, T Nakanishi - Journal of the American …, 2007 - ACS Publications
BF2 complexes of aryl-substituted dipyrrolyldiketones (3a− c, 5a− d) have been synthesized
by the condensation of arylpyrroles obtained by Suzuki cross-coupling reactions with …