Nirmatrelvir/Ritonavir Regimen for Mild/Moderately Severe COVID-19: A Rapid Review With Meta-Analysis and Trial Sequential Analysis

GN Okoli, N Askin, R Rabbani - The Annals of Family Medicine, 2024 - annfammed.org
BACKGROUND The efficacy, effectiveness, and safety of the approved nirmatrelvir/ritonavir
regimen for treatment of laboratory-confirmed mild/moderately severe COVID-19 remains …

The impact of vaccination and outpatient treatment on the economic burden of COVID-19 in the United States omicron era: a systematic literature review

V Pierre, F Draica, M Di Fusco, J Yang… - Journal of Medical …, 2023 - Taylor & Francis
Aims To identify and synthesize evidence regarding how coronavirus disease 2019 (COVID-
19) interventions, including vaccines and outpatient treatments, have impacted healthcare …

Effectiveness of nirmatrelvir‐ritonavir on severe outcomes of COVID‐19 in the era of vaccination and Omicron: An updated meta‐analysis

S Ombelet, D Castanares‐Zapatero… - Journal of medical …, 2024 - Wiley Online Library
Nirmatrelvir‐ritonavir (NR) was approved to treat SARS‐CoV‐2 positive outpatients at high
risk of progression to severe disease, based on a randomized trial in unvaccinated patients …

A review on the impact of the SARS-CoV-2 Omicron subvariant on elderly patients with diverse co-morbidities

A Khadela, S Soni, K Megha, S Bhagat, VP Chavda - Biologics, 2023 - mdpi.com
The SARS-CoV-2 virus has caused a catastrophic impact on the world for the past 3 years.
The virus has now returned with the emergence of the Omicron (B. 1.1. 529) variant. Within …

Outpatient Treatment of Confirmed COVID-19: A Living, Rapid Evidence Review for the American College of Physicians (Version 2, Update Alert)

I Sommer, AI Dobrescu, E Persad… - Annals of Internal …, 2024 - acpjournals.org
This first update alert reports surveillance results of the living, rapid evidence review on
“Outpatient Treatment of Confirmed COVID-19: A Living, Rapid Evidence Review for the …

Clinical Outcome and 7-Day Virological Clearance in High-Risk Patients with Mild–Moderate COVID-19 Treated with Molnupiravir, Nirmatrelvir/Ritonavir, or …

F Bai, T Beringheli, V Vitaletti, A Santoro, F Molà… - Infectious Diseases and …, 2024 - Springer
Introduction We compared the effectiveness and virological clearance (VC) at day 7 (T7)
post-treatment with molnupiravir, nirmatrelvir/ritonavir, and remdesivir in SARS-CoV-2 …

Approaches to pandemic prevention–the chromatin vaccine

J Zhang, P Askenase, R Jaenisch… - Frontiers in …, 2023 - frontiersin.org
Developing effective vaccines against viral infections have significant impacts on
development, prosperity and well-being of human populations. Thus, successful vaccines …

Comparing the effectiveness of molnupiravir and nirmatrelvir‐ritonavir in non‐hospitalized and hospitalized COVID‐19 patients with type 2 diabetes: A target trial …

EYF Wan, ZCT Wong, VKC Yan… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aims To compare the effectiveness of molnupiravir and nirmatrelvir‐ritonavir for non‐
hospitalized and hospitalized COVID‐19 patients with type 2 diabetes (T2DM). Materials …

Comparative analysis of the safety and effectiveness of Nirmatrelvir-Ritonavir and Azvudine in older patients with COVID-19: a retrospective study from a tertiary …

N Shang, X Li, Z Guo, L Zhang, S Wang - Frontiers in Pharmacology, 2024 - frontiersin.org
Introduction: Numerous studies have explored the treatment outcomes of Nirmatrelvir-
Ritonavir and Azvudine in older patients with COVID-19. However, direct comparisons …

[PDF][PDF] Nirmatrelvir-Ritonavir for the Treatment of COVID-19

N Eze, B Asante, C Spry, F Clement - 2023 - researchgate.net
The findings suggest nirmatrelvir-ritonavir reduces the risk of disease progression,
hospitalization, or death compared to placebo or standard of care in people with mild to …