Highlights•Enterococcus faecium is gaining prominence as a nosocomial pathogen.•Genome expansion is a distinguishing feature of health-care associated E …
CA Arias, D Panesso, DM McGrath, X Qin… - … England Journal of …, 2011 - Mass Medical Soc
Background Daptomycin is a lipopeptide with bactericidal activity that acts on the cell membrane of enterococci and is often used off-label to treat patients infected with …
TT Tran, D Panesso, NN Mishra, E Mileykovskaya… - MBio, 2013 - Am Soc Microbiol
Treatment of multidrug-resistant enterococci has become a challenging clinical problem in hospitals around the world due to the lack of reliable therapeutic options. Daptomycin (DAP) …
HMS Goh, MHA Yong, KKL Chong, KA Kline - Virulence, 2017 - Taylor & Francis
Enterococcus faecalis and Enterococcus faecium are common inhabitants of the human gastrointestinal tract, as well as frequent opportunistic pathogens. Enterococci cause a …
X Qin, JR Galloway-Peña, J Sillanpaa, JH Roh… - BMC microbiology, 2012 - Springer
Background Enterococci are among the leading causes of hospital-acquired infections in the United States and Europe, with Enterococcus faecalis and Enterococcus faecium being the …
DB Clewell, KE Weaver, GM Dunny… - … : From commensals to …, 2014 - ncbi.nlm.nih.gov
Extrachromosomal elements are ubiquitous in the prokaryotic world and play important roles in the adaptation and survival of cell populations, especially in changing environments …
A Khan, M Davlieva, D Panesso… - Proceedings of the …, 2019 - National Acad Sciences
Bacteria have developed several evolutionary strategies to protect their cell membranes (CMs) from the attack of antibiotics and antimicrobial peptides (AMPs) produced by the …
TT Tran, D Panesso, H Gao, JH Roh… - Antimicrobial agents …, 2013 - Am Soc Microbiol
Development of daptomycin (DAP) resistance in Enterococcus faecalis has recently been associated with mutations in genes encoding proteins with two main functions:(i) control of …
Firmicutes constitutes one of the dominant bacteria phyla of human and animal gut microbiota. It comprises a number of genera of outstanding relevance in health care and …