Image-based profiling is a maturing strategy by which the rich information present in
biological images is reduced to a multidimensional profile, a collection of extracted image …

As a promising in vivo tool for cancer research, zebrafish have been widely applied in
various tumor studies. The zebrafish xenograft model is a low-cost, high-throughput tool for …

Simple Summary The current article provides an overview of the significance of using
various mouse and zebrafish models in cancer research. In addition, this review discusses …

Animal models contribute greatly to our understanding of brain development and function as
well as its dysfunction in neurological diseases. Epilepsy research is a very good example of …

Patient‐derived tumor xenograft (PDX) models, a method involving the surgical extraction of
tumor tissues from cancer patients and subsequent transplantation into immunodeficient …

The increasing number of available anti-cancer drugs presents a challenge for oncologists,
who must choose the most effective treatment for the patient. Precision cancer medicine …

Zebrafish xenotransplantation models are increasingly applied for phenotypic drug
screening to identify small compounds for precision oncology. Larval zebrafish xenografts …

Simple Summary The identification and development of new anti-cancer drugs requires
extensive testing in animal models to establish safety and efficacy of drug candidates. The …

Head and neck cancers (HNCs) represent the sixth most widespread malignancy worldwide.
Surgery, radiotherapy, chemotherapeutic and immunotherapeutic drugs represent the main …

The first steps towards establishing xenografts in zebrafish embryos were performed by Lee
et al., 2005 and Haldi et al., 2006, paving the way for studying human cancers using this …