Genetic load: genomic estimates and applications in non-model animals

G Bertorelle, F Raffini, M Bosse, C Bortoluzzi… - Nature Reviews …, 2022 - nature.com
Genetic variation, which is generated by mutation, recombination and gene flow, can reduce
the mean fitness of a population, both now and in the future. This 'genetic load'has been …

Evolution of life in urban environments

MTJ Johnson, J Munshi-South - Science, 2017 - science.org
BACKGROUND The extent of urban areas is increasing around the world, and most humans
now live in cities. Urbanization results in dramatic environmental change, including …

Three problems in the genetics of speciation by selection

D Schluter, LH Rieseberg - Proceedings of the National …, 2022 - National Acad Sciences
Speciation is the process by which barriers to gene flow evolve between populations.
Although we now know that speciation is largely driven by natural selection, knowledge of …

New developments in the field of genomic technologies and their relevance to conservation management

G Segelbacher, M Bosse, P Burger, P Galbusera… - Conservation …, 2022 - Springer
Recent technological advances in the field of genomics offer conservation managers and
practitioners new tools to explore for conservation applications. Many of these tools are well …

Spindle asymmetry drives non-Mendelian chromosome segregation

T Akera, L Chmátal, E Trimm, K Yang, C Aonbangkhen… - Science, 2017 - science.org
Genetic elements compete for transmission through meiosis, when haploid gametes are
created from a diploid parent. Selfish elements can enhance their transmission through a …

From molecules to populations: appreciating and estimating recombination rate variation

JV Peñalba, JBW Wolf - Nature Reviews Genetics, 2020 - nature.com
Recombination is a central biological process with implications for many areas in the life
sciences. Yet we are only beginning to appreciate variation in the recombination rate along …

Mutation pressure, drift, and the pace of molecular coevolution

M Lynch - Proceedings of the National Academy of …, 2023 - National Acad Sciences
Most aspects of the molecular biology of cells involve tightly coordinated intermolecular
interactions requiring specific recognition at the nucleotide and/or amino acid levels. This …

Meiotic drive mechanisms: lessons from Drosophila

C Courret, CH Chang, KHC Wei… - … of the Royal …, 2019 - royalsocietypublishing.org
Meiotic drivers are selfish genetic elements that bias their transmission into gametes, often
to the detriment of the rest of the genome. The resulting intragenomic conflicts triggered by …

Genetic conflicts: the usual suspects and beyond

RN McLaughlin Jr, HS Malik - Journal of Experimental …, 2017 - journals.biologists.com
Selfishness is pervasive and manifests at all scales of biology, from societies, to individuals,
to genetic elements within a genome. The relentless struggle to seek evolutionary …

Evolution of bird genomes—a transposon's‐eye view

A Kapusta, A Suh - Annals of the New York Academy of …, 2017 - Wiley Online Library
Birds, the most species‐rich monophyletic group of land vertebrates, have been subject to
some of the most intense sequencing efforts to date, making them an ideal case study for …