Towards a future where Alzheimer's disease pathology is stopped before the onset of dementia

WM van der Flier, ME de Vugt, EMA Smets, M Blom… - Nature aging, 2023 - nature.com
Alzheimer's disease (AD) is a major healthcare challenge with no curative treatment at
present. To address this challenge, we need a paradigm shift, where we focus on pre …

DementiaBank: Theoretical rationale, protocol, and illustrative analyses

AM Lanzi, AK Saylor, D Fromm, H Liu… - American Journal of …, 2023 - ASHA
Purpose: Dementia from Alzheimer's disease (AD) is characterized primarily by a significant
decline in memory abilities; however, language abilities are also commonly affected and …

Definitions of digital biomarkers: a systematic mapping of the biomedical literature

AKM Alonso, J Hirt, T Woelfle, P Janiaud, LG Hemkens - medRxiv, 2023 - medrxiv.org
Background Technological devices such as smartphones, wearables, sensors, or virtual
assistants allow to collect data on health and disease processes and are thus increasingly …

Variable STFT layered CNN model for automated dysarthria detection and severity assessment using raw speech

K Radha, M Bansal, VR Dhulipalla - Circuits, Systems, and Signal …, 2024 - Springer
This paper presents a novel approach for automated dysarthria detection and severity
assessment using a variable short-time Fourier transform layered convolutional neural …

Automatic dysarthria detection and severity level assessment using CWT-layered CNN model

S Sajiha, K Radha, D Venkata Rao, N Sneha… - EURASIP Journal on …, 2024 - Springer
Dysarthria is a speech disorder that affects the ability to communicate due to articulation
difficulties. This research proposes a novel method for automatic dysarthria detection (ADD) …

Automated Measures of Syntactic Complexity in Natural Speech Production: Older and Younger Adults as a Case Study

G Agmon, S Pradhan, S Ash, N Nevler… - Journal of Speech …, 2024 - ASHA
Purpose: Multiple methods have been suggested for quantifying syntactic complexity in
speech. We compared eight automated syntactic complexity metrics to determine which best …

Mild cognitive impairment identification based on motor and cognitive dual-task pooled indices

G Mancioppi, E Rovini, L Fiorini, R Zeghari, A Gros… - Plos one, 2023 - journals.plos.org
Objective This study investigates the possibility of adopting motor and cognitive dual-task
(MCDT) approaches to identify subjects with mild cognitive impairment (MCI) and subjective …

Automated detection and severity assessment of dysarthria using raw speech

K Radha, M Bansal - 2023 14th International Conference on …, 2023 - ieeexplore.ieee.org
Dysarthria is a medical condition that impairs an individual's ability to speak clearly due to
muscle weakness or paralysis. To diagnose and monitor dysarthria severity, this article …

The California Cognitive Assessment Battery (CCAB)

D Woods, P Pebler, DK Johnson, T Herron… - Frontiers in Human …, 2024 - frontiersin.org
Introduction We are developing the California Cognitive Assessment Battery (CCAB) to
provide neuropsychological assessments to patients who lack test access due to cost …

A novel speech analysis algorithm to detect cognitive impairment in a Spanish population

AN Kaser, LH Lacritz, HR Winiarski… - Frontiers in …, 2024 - frontiersin.org
Objective Early detection of cognitive impairment in the elderly is crucial for diagnosis and
appropriate care. Brief, cost-effective cognitive screening instruments are needed to help …