Overview of the 2022 WHO classification of thyroid neoplasms
This review summarizes the changes in the 5th edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new …
Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new …
Update on fundamental mechanisms of thyroid cancer
A Prete, P Borges de Souza, S Censi… - Frontiers in …, 2020 - frontiersin.org
The incidence of thyroid cancer (TC) has increased worldwide over the past four decades.
TC is divided into three main histological types: differentiated (papillary and follicular TC) …
TC is divided into three main histological types: differentiated (papillary and follicular TC) …
The American Association of Endocrine Surgeons guidelines for the definitive surgical management of thyroid disease in adults
KN Patel, L Yip, CC Lubitz, EG Grubbs, BS Miller… - Annals of …, 2020 - journals.lww.com
Objective: To develop evidence-based recommendations for safe, effective, and appropriate
thyroidectomy. Background: Surgical management of thyroid disease has evolved …
thyroidectomy. Background: Surgical management of thyroid disease has evolved …
Thyroid cancer: a review
L Boucai, M Zafereo, ME Cabanillas - Jama, 2024 - jamanetwork.com
Importance Approximately 43 720 new cases of thyroid carcinoma are expected to be
diagnosed in 2023 in the US. Five-year relative survival is approximately 98.5%. This review …
diagnosed in 2023 in the US. Five-year relative survival is approximately 98.5%. This review …
Pathogenesis of cancers derived from thyroid follicular cells
The genomic simplicity of differentiated cancers derived from thyroid follicular cells offers
unique insights into how oncogenic drivers impact tumour phenotype. Essentially, the main …
unique insights into how oncogenic drivers impact tumour phenotype. Essentially, the main …
Emerging biomarkers in thyroid practice and research
Simple Summary Tumor biomarkers are molecules at genetic or protein level, or certain
evaluable characteristics. These help in perfecting patient management. Over the past …
evaluable characteristics. These help in perfecting patient management. Over the past …
A narrative review of genetic alterations in primary thyroid epithelial cancer
C Romei, R Elisei - International journal of molecular sciences, 2021 - mdpi.com
Thyroid carcinoma is the most frequent endocrine neoplasia. Different types of thyroid
carcinoma are described: well-differentiated papillary thyroid carcinoma (PTC), poorly …
carcinoma are described: well-differentiated papillary thyroid carcinoma (PTC), poorly …
Genomic alterations in thyroid cancer: biological and clinical insights
I Landa, ME Cabanillas - Nature Reviews Endocrinology, 2024 - nature.com
Tumours can arise from thyroid follicular cells if they acquire driver mutations that
constitutively activate the MAPK signalling pathway. In addition, a limited set of additional …
constitutively activate the MAPK signalling pathway. In addition, a limited set of additional …
The genomic landscape of thyroid cancer tumourigenesis and implications for immunotherapy
A Singh, J Ham, JW Po, N Niles, T Roberts, CS Lee - Cells, 2021 - mdpi.com
Thyroid cancer is the most prevalent endocrine malignancy that comprises mostly indolent
differentiated cancers (DTCs) and less frequently aggressive poorly differentiated (PDTC) or …
differentiated cancers (DTCs) and less frequently aggressive poorly differentiated (PDTC) or …
Mechanistic insights of thyroid cancer progression
LJ Leandro-García, I Landa - Endocrinology, 2023 - academic.oup.com
Differentiated thyroid cancers (DTCs) are primarily initiated by mutations that activate the
MAPK signaling cascade, typically at BRAF or RAS oncoproteins. DTCs can evolve to more …
MAPK signaling cascade, typically at BRAF or RAS oncoproteins. DTCs can evolve to more …