2004 Nature Pub lishing Group http://www. nature. com/natureneuroscience the axon
terminals in the striatum (Fig. 1d) or through the lateral ventricular route. Once rescued, the …

Several exciting approaches for restorative therapy in Parkinson's disease have emerged
over the past two decades. This review initially describes experimental and clinical data …

The effects of continuous glial cell line-derived neurotrophic factor (GDNF) overexpression
in the intact nigrostriatal dopamine (DA) system was studied using recombinant lentiviral …

Previously, we demonstrated that the action of the natural alkaloid, ibogaine, to reduce
alcohol (ethanol) consumption is mediated by the glial cell line-derived neurotrophic factor …

We used a model system in which dopaminergic (DA) neurons from embryonic rat
mesencephalon undergo spontaneous and selective degeneration as they develop in …

Globus pallidus (GP) neurons recorded in brain slices show significant variability in intrinsic
electrophysiological properties. To investigate how this variability arises, we manipulated …

Glial cell line-derived neurotrophic factor (GDNF) is widely recognized as a potent survival
factor for dopaminergic neurons of the nigrostriatal pathway that degenerate in Parkinson's …

We previously found that activation of the glial cell line–derived neurotrophic factor (GDNF)
pathway in the ventral tegmental area (VTA) reduces moderate alcohol (ethanol) intake in a …

Ret signaling is critical for formation of the enteric nervous system (ENS) because Ret
activation promotes ENS precursor survival, proliferation, and migration and provides trophic …

The glial cell line-derived neurotrophic factor (GDNF) is a secreted protein, best known for its
role in the development of the central and peripheral nervous systems and the survival of …