Female breast cancer is the world's most prevalent cancer in 2020. Chemotherapy still
remains a backbone in breast cancer therapy and is crucial in advanced and metastatic …

The use of nanotechnology in targeted drug delivery systems (DDS) is the subject of
extensive investigations due to limitations associated with traditional forms of drug delivery …

Background The systemic administration of cytotoxic chemotherapeutic agents for cancer
treatment often has toxic side effects, limiting the usage dose. To increase chemotherapeutic …

Chemotherapy is widely used for cancer therapy; however, its efficacy is limited due to poor
targeting specificity and severe side effects. Currently, the next generations of delivery …

The main transporter for biotin is sodium dependent multivitamin transporter (SMVT), which
is overexpressed in various aggressive cancer cell lines such as ovarian (OV 2008, ID8) …

Paclitaxel (PTX) is a chemotherapeutical agent commonly used to treat several kinds of
cancer. PTX is known as a microtubule-targeting agent with a primary molecular mechanism …

Multidrug resistance (MDR) is a major obstacle to successful cancer therapy, especially for
chemotherapy. Endogenous stimulus-responsive nanosystems (ESRNs), which were …

The objective of the work was to develop a multifunctional nanomedicine based on a folate-
conjugated lipid nanoparticles loaded with paclitaxel and curcumin. The novel system …

Quantum dots are nanoparticles, which due to their unique physical and chemical (first of all
optical) properties, are promising in biology and medicine. There are many ways for …

Multidrug resistance (MDR) presents a serious challenge to the efficiency of cancer
treatment, and may be associated with the overexpression of drug efflux pumps. P …