[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …

COVID-19 and the promise of small molecule therapeutics: Are there lessons to be learnt?

WS Ho, R Zhang, YL Tan, CLL Chai - Pharmacological Research, 2022 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic had grounded the world to a
standstill. As the disease continues to rage two years on, it is apparent that effective …

Comparing efficacy and safety of different doses of dexamethasone in the treatment of COVID-19: a three-arm randomized clinical trial

N Toroghi, L Abbasian, A Nourian… - Pharmacological …, 2022 - Springer
Background and objectives Corticosteroids are commonly used in the treatment of
hospitalized patients with COVID-19. The goals of the present study were to compare the …

COVID-19 detection in chest X-ray images using a new channel boosted CNN

SH Khan, A Sohail, A Khan, YS Lee - Diagnostics, 2022 - mdpi.com
COVID-19 is a respiratory illness that has affected a large population worldwide and
continues to have devastating consequences. It is imperative to detect COVID-19 at the …

Deciphering SARS-CoV-2 virologic and immunologic features

G Lebeau, D Vagner, E Frumence, F Ah-Pine… - International journal of …, 2020 - mdpi.com
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 and its associated
pathology, COVID-19, have been of particular concerns these last months due to the …

[HTML][HTML] Current systematic reviews and meta-analyses of COVID-19

M Nassar, N Nso, M Alfishawy, A Novikov… - World Journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Coronavirus disease 2019 (COVID-19) has left a significant impact on the
world's health, economic and political systems; as of November 20, 2020, more than 57 …

COVID-19 treatment guidelines: do they really reflect best medical practices to manage the pandemic?

F Jirjees, AK Saad, Z Al Hano, T Hatahet… - Infectious Disease …, 2021 - mdpi.com
SARS-CoV-2 (COVID-19) has been changing the world since December 2019. A
comprehensive search into many COVID-19 treatment guidelines was conducted and …

Do high‐dose corticosteroids improve outcomes in hospitalized COVID‐19 patients?

G Kumar, D Patel, M Hererra, D Jefferies… - Journal of Medical …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is characterized by dysregulated
hyperimmune response and steroids have been shown to decrease mortality. However …

Four waves of the COVID-19 pandemic: comparison of clinical and pregnancy outcomes

S Mihajlovic, D Nikolic, M Santric-Milicevic, B Milicic… - Viruses, 2022 - mdpi.com
During the last two and a half years, clinical manifestations, disease severity, and pregnancy
outcomes have differed among pregnant patients with SARS-CoV-2 infection. These …

[HTML][HTML] Machine learning as a precision-medicine approach to prescribing COVID-19 pharmacotherapy with remdesivir or corticosteroids

C Lam, A Siefkas, NS Zelin, G Barnes, RP Dellinger… - Clinical …, 2021 - Elsevier
Abstract Purpose: Coronavirus disease–2019 (COVID-19) continues to be a global threat
and remains a significant cause of hospitalizations. Recent clinical guidelines have …