Rapid removal of apoptotic cells by phagocytes, a process known as efferocytosis, is key for
the maintenance of tissue homeostasis, the resolution of inflammation, and tissue repair …

Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …

Experimental studies reported biochemical actions underpinning aging processes and
mortality, but the relevant metabolic alterations in humans are not well understood. Here we …

Aging of the vasculature, which is integral to the functioning of literally all human organs,
serves as a fundamental physiological basis for age-related alterations as well as a shared …

Metabolomics, the global profiling of small molecules in the body, has emerged as a
promising analytical approach for assessing molecular changes associated with ageing at …

Aging process is characterized by a progressive decline of several organic, physiological,
and metabolic functions whose precise mechanism remains unclear. Metabolomics allows …

Background The three-layered meninges cover and protect the central nervous system and
form the interface between cerebrospinal fluid and the brain. They are host to a lymphatic …

Metabolite profiling serves as a powerful tool that advances our understanding of biological
systems, disease mechanisms, and environmental interactions. In this study, we present an …

Given the unprecedented phenomenon of population ageing, studies have increasing
captured the heterogeneity within the ageing process. In this context, the concept of …

The aging population and high incidence of age-related diseases are major global societal
issues. Consuming bioactive substances as part of our diet is increasingly recognized as …