Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …

Cancer immunotherapy has achieved promising clinical progress over the recent years for
its potential to treat metastatic tumors and inhibit their recurrences effectively. However, low …

The immunologically “cold” microenvironment of triple negative breast cancer results in
resistance to current immunotherapy. Here, we reveal the immunoadjuvant property of gas …

Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Catalysis and medicine are often considered as two independent research fields with their
own respective scientific phenomena. Promoted by recent advances in nanochemistry, large …

In view of certain unique internalization features of the tumor microenvironment
(TME)(mainly including hypoxia, acidity and higher concentrations of H 2 O 2 and GSH) …

Endoplasmic reticulum (ER) stress, caused by overproduction of reactive oxygen species
(ROS), has been shown to be responsible for immunogenic cell death (ICD). Seeking ROS …

Nano‐immunotherapy has been recognized as a highly promising strategy for cancer
treatment in recent decades, which combines nanotechnology and immunotherapy to …

Despite the widespread applications of manganese oxide nanomaterials (MONs) in
biomedicine, the intrinsic immunogenicity of MONs is still unclear. MnOx nanospikes (NSs) …

Current chemodynamic therapy (CDT) primarily relies on the delivery of transition metal ions
with Fenton activity to trigger hydroxyl radical production from hydrogen peroxide. However …