Comparative pathobiology of canine and human prostate cancer: state of the art and future directions

EP Nascente, RL Amorim, CE Fonseca-Alves… - Cancers, 2022 - mdpi.com
Simple Summary Prostate cancer (PC) is one of the main types of cancer that affects the
male population worldwide. In recent decades, there has been a significant evolution in the …

Molecular Similarities and Differences between Canine Prostate Cancer and Human Prostate Cancer Variants

DM Vasilatis, CA Lucchesi, PM Ghosh - Biomedicines, 2023 - mdpi.com
Dogs are one of few species that naturally develop prostate cancer (PCa), which clinically
resembles aggressive, advanced PCa in humans. Moreover, PCa-tumor samples from dogs …

An RNA-Seq-based framework for characterizing canine prostate cancer and prioritizing clinically relevant biomarker candidate genes

H Thiemeyer, L Taher, JT Schille, EM Packeiser… - International journal of …, 2021 - mdpi.com
Prostate cancer (PCa) in dogs is a highly malignant disease akin to its human counterpart. In
contrast to the situation in humans, multi-gene approaches facilitating risk stratification of …

P-Glycoprotein and Androgen Receptor Expression Reveals Independence of Canine Prostate Cancer from Androgen Hormone Stimulation

AMB Cavalca, A Brandi, RH Fonseca-Alves… - International Journal of …, 2022 - mdpi.com
Canine prostate cancer (PC) is an aggressive disease, and dogs can be considered
comparative models for human PC. In recent years, canine PC has been shown to resemble …

Lifelong exercise training promotes the remodelling of the immune system and prostate signalome in a rat model of prostate carcinogenesis

E Nascimento-Gonçalves, F Seixas, C Palmeira… - GeroScience, 2024 - Springer
This work aimed to understand how lifelong exercise training promotes the remodelling of
the immune system and prostate signalome in a rat model of PCa. Fifty-five male Wistar rats …