Adaptive immune responses and immunity to SARS-CoV-2
Since the onset of the COVID-19 pandemic, the medical field has been forced to apply the
basic knowledge of immunology with the most up-to-date SARS-CoV-2 findings and …
basic knowledge of immunology with the most up-to-date SARS-CoV-2 findings and …
COVID-19 mechanisms in the human body—What we know so far
More than one and a half years have elapsed since the commencement of the coronavirus
disease 2019 (COVID-19) pandemic, and the world is struggling to contain it. Being caused …
disease 2019 (COVID-19) pandemic, and the world is struggling to contain it. Being caused …
Cross-tissue immune cell analysis reveals tissue-specific features in humans
C Domínguez Conde, C Xu, LB Jarvis, DB Rainbow… - Science, 2022 - science.org
Despite their crucial role in health and disease, our knowledge of immune cells within
human tissues remains limited. We surveyed the immune compartment of 16 tissues from 12 …
human tissues remains limited. We surveyed the immune compartment of 16 tissues from 12 …
The IL-1β, IL-6, and TNF cytokine triad is associated with post-acute sequelae of COVID-19
C Schultheiß, E Willscher, L Paschold, C Gottschick… - Cell Reports …, 2022 - cell.com
Post-acute sequelae of COVID-19 (PASC) is emerging as global problem with unknown
molecular drivers. Using a digital epidemiology approach, we recruited 8,077 individuals to …
molecular drivers. Using a digital epidemiology approach, we recruited 8,077 individuals to …
Dexamethasone modulates immature neutrophils and interferon programming in severe COVID-19
Although critical for host defense, innate immune cells are also pathologic drivers of acute
respiratory distress syndrome (ARDS). Innate immune dynamics during Coronavirus …
respiratory distress syndrome (ARDS). Innate immune dynamics during Coronavirus …
Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19
RS Thwaites, A Sanchez Sevilla Uruchurtu… - Science …, 2021 - science.org
While it is now widely accepted that host inflammatory responses contribute to lung injury,
the pathways that drive severity and distinguish coronavirus disease 2019 (COVID-19) from …
the pathways that drive severity and distinguish coronavirus disease 2019 (COVID-19) from …
Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19
AHE Roukens, CR Pothast, M König, W Huisman… - Nature …, 2022 - nature.com
Systemic immune cell dynamics during coronavirus disease 2019 (COVID-19) are
extensively documented, but these are less well studied in the (upper) respiratory tract …
extensively documented, but these are less well studied in the (upper) respiratory tract …
[HTML][HTML] Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia
Immune profiling of COVID-19 patients has identified numerous alterations in both innate
and adaptive immunity. However, whether those changes are specific to SARS-CoV-2 or …
and adaptive immunity. However, whether those changes are specific to SARS-CoV-2 or …
Cytokine storm signature in patients with moderate and severe COVID-19
O Kalinina, A Golovkin, E Zaikova, A Aquino… - International Journal of …, 2022 - mdpi.com
Hypercytokinemia, found in SARS-CoV-2 infection, contributes to multiple organ
dysfunctions with acute respiratory distress syndrome, shock etc. The aim of this study was …
dysfunctions with acute respiratory distress syndrome, shock etc. The aim of this study was …
COVID‐19 immunopathology: from acute diseases to chronic sequelae
The clinical manifestation of coronavirus disease 2019 (COVID‐19) mainly targets the lung
as a primary affected organ, which is also a critical site of immune cell activation by severe …
as a primary affected organ, which is also a critical site of immune cell activation by severe …