Bioinspired stabilization of amorphous calcium carbonate by carboxylated nanocellulose enables mechanically robust, healable, and Sensing biocomposites

W Wu, Z Lu, C Lu, X Sun, B Ni, H Cölfen, R Xiong - ACS nano, 2023 - ACS Publications
Nature builds numerous structurally complex composites with fascinating mechanical
robustness and functionalities by harnessing biopolymers and amorphous calcium …

Biodegradable Nanoparticles of Polyacrylic Acid–Stabilized Amorphous CaCO3 for Tunable pH‐Responsive Drug Delivery and Enhanced Tumor Inhibition

C Xu, Y Yan, J Tan, D Yang, X Jia… - Advanced Functional …, 2019 - Wiley Online Library
Inorganic nanoparticles (NPs) are promising drug delivery carriers owing to their high drug
loading efficiency, scalable preparation, facile functionalization, and chemical/thermal …

[HTML][HTML] Unlocking the potential of amorphous calcium carbonate: A star ascending in the realm of biomedical application

H Liu, Z Wen, Z Liu, Y Yang, H Wang, X Xia, J Ye… - … Pharmaceutica Sinica B, 2024 - Elsevier
Calcium-based biomaterials have been intensively studied in the field of drug delivery owing
to their excellent biocompatibility and biodegradability. Calcium-based materials can also …

Biomineralization-inspired functional biomaterials: From principles to practice

H Hu, Y Lin, B Yang, X Wen, P Ma, XJ Loh… - Chemical Engineering …, 2024 - Elsevier
Biomineralization is a process by which organisms regulate the combination of organic and
inorganic matter to build functional organic–inorganic hybrid materials. Due to their precise …

Collagen piezoelectricity in osteogenesis imperfecta and its role in intrafibrillar mineralization

J Kwon, H Cho - Communications Biology, 2022 - nature.com
Intrafibrillar mineralization plays a critical role in attaining desired mechanical properties of
bone. It is well known that amorphous calcium phosphate (ACP) infiltrates into the collagen …

Microwave hydrothermal transformation of amorphous calcium carbonate nanospheres and application in protein adsorption

C Qi, YJ Zhu, F Chen - ACS Applied Materials & Interfaces, 2014 - ACS Publications
Calcium carbonate and calcium phosphate are the main components of biominerals. Among
all of the forms of biominerals, amorphous calcium carbonate (ACC) and amorphous …

Alginate-assisted mineralization of collagen by collagen reconstitution and calcium phosphate formation

W Su, L Ma, Y Ran, X Ma, Z Yi, G Chen… - ACS Biomaterials …, 2020 - ACS Publications
The understanding of the mineralization of collagen for bone formation is a current key
theme in bone tissue engineering and is of great relevance to the fabrication of novel …

Biomimetic synthesis of calcium carbonate with different morphologies and polymorphs in the presence of bovine serum albumin and soluble starch

Y Liu, Y Chen, X Huang, G Wu - Materials Science and Engineering: C, 2017 - Elsevier
Calcium carbonate has been synthesized by the reaction of Na 2 CO 3 and CaCl 2 in the
presence of bovine serum albumin (BSA) and soluble starch. Effects of various bovine …

Amorphous calcium carbonate based-microparticles for peptide pulmonary delivery

F Tewes, OL Gobbo, C Ehrhardt… - ACS applied materials & …, 2016 - ACS Publications
Amorphous calcium carbonate (ACC) is known to interact with proteins, for example, in
biogenic ACC, to form stable amorphous phases. The control of amorphous/crystalline and …

Fibril formation pH controls intrafibrillar collagen biomineralization in vitro and in vivo

B Marelli, CE Ghezzi, YL Zhang, I Rouiller, JE Barralet… - Biomaterials, 2015 - Elsevier
We demonstrate that intrafibrillar, homogenous collagen biomineralization can be achieved
by controlling self-assembly under mildly alkaline conditions. Using dense collagen (DC) …