The EASL–Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality

TH Karlsen, N Sheron, S Zelber-Sagi, P Carrieri… - The Lancet, 2022 - thelancet.com
Executive summary Liver diseases have become a major health threat across Europe, and
the face of European hepatology is changing due to the cure of viral hepatitis C and the …

[HTML][HTML] Childhood and adolescent obesity: a review

AR Kansra, S Lakkunarajah, MS Jay - Frontiers in pediatrics, 2021 - frontiersin.org
Obesity is a complex condition that interweaves biological, developmental, environmental,
behavioral, and genetic factors; it is a significant public health problem. The most common …

Clinical practice guideline for the evaluation and treatment of children and adolescents with obesity

SE Hampl, SG Hassink, AC Skinner, SC Armstrong… - …, 2023 - publications.aap.org
You have in your hands, or at your fingertips, the first edition of the American Academy of
Pediatrics clinical practice guideline for evaluation and management of children and …

Defining paediatric metabolic (dysfunction)-associated fatty liver disease: an international expert consensus statement

M Eslam, N Alkhouri, P Vajro, U Baumann… - The Lancet …, 2021 - thelancet.com
The term non-alcoholic fatty liver disease (NAFLD), and its definition, have limitations for
both adults and children. The definition is most problematic for children, for whom alcohol …

The diagnosis and management of nonalcoholic fatty liver disease: practice guidance from the American Association for the Study of Liver Diseases

N Chalasani, Z Younossi, JE Lavine, M Charlton… - Hepatology, 2018 - journals.lww.com
This guidance provides a data‐supported approach to the diagnostic, therapeutic, and
preventive aspects of nonalcoholic fatty liver disease (NAFLD) care. A “Guidance” document …

Fibrosis severity as a determinant of cause-specific mortality in patients with advanced nonalcoholic fatty liver disease: a multi-national cohort study

E Vilar-Gomez, L Calzadilla-Bertot, VWS Wong… - Gastroenterology, 2018 - Elsevier
Background & Aims Little is known about the natural course of nonalcoholic fatty liver
disease (NAFLD) with advanced fibrosis. We describe long-term outcomes and evaluate the …

NASPGHAN clinical practice guideline for the diagnosis and treatment of nonalcoholic fatty liver disease in children: recommendations from the Expert Committee on …

MB Vos, SH Abrams, SE Barlow, S Caprio… - Journal of pediatric …, 2017 - journals.lww.com
Nonalcoholic fatty liver disease (NAFLD) is a highly prevalent chronic liver disease that
occurs in the setting of insulin resistance and increased adiposity. It has rapidly evolved into …

Non-alcoholic steatohepatitis: a review of its mechanism, models and medical treatments

C Peng, AG Stewart, OL Woodman… - Frontiers in …, 2020 - frontiersin.org
Non-alcoholic steatohepatitis (NASH) develops from non-alcoholic fatty liver disease
(NAFLD). Currently, around 25% of the population is estimated to have NAFLD, and 25% of …

EASL-EASD-EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease

European Association for the Study of the Liver (EASL) … - Obesity facts, 2016 - karger.com
The Clinical Practice Guidelines (CPG) propose recommendations for the diagnosis,
treatment and follow-up of non-alcoholic fatty liver disease (NAFLD) patients and are the …

Nonalcoholic fatty liver disease

EM Brunt, VWS Wong, V Nobili, CP Day… - Nature reviews Disease …, 2015 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is a disorder characterized by excess accumulation
of fat in hepatocytes (nonalcoholic fatty liver (NAFL)); in up to 40% of individuals, there are …