This work proposes an innovative methodology to control high density fed-batch cultures of
E. coli, based on measurements of the concentration of dissolved oxygen and on …

This is an introductory chapter that presents a general review of some Computational
Intelligence (CI) techniques used today, both in the biotechnology industry and in academic …

This chapter presents and discusses several well-known constructive neural network
algorithms suitable for constructing feedforward architectures aiming at classification tasks …

One of the most important events in fed-batch fermentations is the definition of the moment to
start the feeding. This paper presents a methodology for a rational selection of the …

Under different environmental conditions, microbial systems display complex behavioral
patterns that are difficult to express quantitatively by mechanistic methods. Therefore, two …

High cell density cultivations of recombinant E. coli are a fast and economical way to
produce recombinant proteins. Through this bioprocess, products with high added value and …

Streptococcus pneumoniae is a bacterial pathogen that causes many life-threatening
diseases and an effective vaccine against this pa-thogen is still subject of research. These …

Streptococcus pneumoniae (pneumococcus) is a bacterium responsible for a wide spectrum
of illnesses. The surface of the bacterium consists of three distinctive membranes: plasmatic …

Microbioreactors operated in real environments are often subject to noise from the
environment. This is commonly manifested as fluctuations in the flow rates of the feed …

Streptococcus pneumoniae (pneumococo) é uma bactéria patogênica causadora de várias
infecções que são agravadas pelo aumento de cepas com resistência aos antibióticos. O …