Mesenchymal stem cell-derived exosomes: applications in regenerative medicine

MD Hade, CN Suire, Z Suo - Cells, 2021 - mdpi.com
Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …

The immune functions of keratinocytes in skin wound healing

M Piipponen, D Li, NX Landén - International journal of molecular …, 2020 - mdpi.com
As the most dominant cell type in the skin, keratinocytes play critical roles in wound repair
not only as structural cells but also exerting important immune functions. This review focuses …

Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing

C Zhou, B Zhang, Y Yang, Q Jiang, T Li, J Gong… - Stem cell research & …, 2023 - Springer
Wound healing is a dynamic and highly sequential process involving a series of overlapping
spatial and temporal phases, including hemostasis, inflammation, proliferation, and tissue …

Biomaterials functionalized with MSC secreted extracellular vesicles and soluble factors for tissue regeneration

MÁ Brennan, P Layrolle… - Advanced functional …, 2020 - Wiley Online Library
The therapeutic benefits of mesenchymal stromal cell (MSC) transplantation are attributed to
their secreted factors, including extracellular vesicles (EVs) and soluble factors. The …

Extracellular vesicles derived from mesenchymal stem cells (MSC) in regenerative medicine: applications in skin wound healing

A Casado-Díaz, JM Quesada-Gómez… - … in Bioengineering and …, 2020 - frontiersin.org
The cells secrete extracellular vesicles (EV) that may have an endosomal origin, or from
evaginations of the plasma membrane. The former are usually called exosomes, with sizes …

Mesenchymal stem cell derived extracellular vesicles for tissue engineering and regenerative medicine applications

D Tsiapalis, L O'Driscoll - Cells, 2020 - mdpi.com
Mesenchymal stem cells (MSCs) are being extensively investigated for their potential in
tissue engineering and regenerative medicine. However, recent evidence suggests that the …

Extracellular vesicles: Emerging frontiers in wound healing

MD Hade, CN Suire, J Mossell… - Medicinal Research …, 2022 - Wiley Online Library
Extracellular vesicles are membranous particles, ranging from 30 nm to 10 µm in diameter,
which are released by nearly all cell types to aid in intercellular communication. These …

The functions and clinical application potential of exosomes derived from adipose mesenchymal stem cells: a comprehensive review

P Hong, H Yang, Y Wu, K Li, Z Tang - Stem cell research & therapy, 2019 - Springer
Exosomes are extracellular membranous nanovesicles that mediate local and systemic
intercellular communication by transporting proteins or nucleic acids (DNA and RNA) into …

Exosome loaded alginate hydrogel promotes tissue regeneration in full‐thickness skin wounds: An in vivo study

S Shafei, M Khanmohammadi, R Heidari… - … Research Part A, 2020 - Wiley Online Library
Wound healing is known as one of the most complicated biological processes for injured
skin caused by surgical, trauma, burns, or diabetic diseases, which causes a nonfunctioning …

Therapeutic applications of adipose cell-free derivatives: a review

Y Cai, J Li, C Jia, Y He, C Deng - Stem Cell Research & Therapy, 2020 - Springer
Background Adipose-derived stem cells (ADSCs) have become one of the most utilized
adult stem cells due to their abundance and accessibility. Recent studies have shown that …