The Mediterranean diet is a plant-based, antioxidant-rich, unsaturated fat dietary pattern that
has been consistently associated with lower rates of noncommunicable diseases and total …

Over two-thirds of individuals aged 65 and older are obese or overweight in the United
States. Epidemiological data show an association between the degree of adiposity and …

Background: Cerebrovascular disease is a common comorbidity in patients with Alzheimer's
disease (AD). It is believed to contribute additively to the cognitive impairment and to lower …

The proportion of elderly populations is rapidly booming, and human lifespan has
considerably increased in the past century because of scientific and medical advances …

Despite the extensive knowledge of the beneficial effects of physical exercise, a sedentary
lifestyle is still a predominant harm in our society. Sedentarism is one of the major modifiable …

The prevalence of depression is higher among people with type 2 diabetes (T2DM).
Individually, both conditions are associated with systemic inflammation. This study aimed to …

Background Excessive blood glucose promotes neuropathological cognitive decline in
individuals with type 2 diabetes mellitus and the metabolic syndrome, but no systematic …

Background and purpose Current evidence supports the involvement of lipids in brain aging.
A range of serum lipids is explored in association with brain structure and cognitive function …

Disruptions to the central excitatory-inhibitory (E/I) balance are thought to be related to aging
and underlie a host of neural pathologies, including Alzheimer's disease. Aging may induce …

After stroke, dynamic changes take place from necrotic-apoptotic continuum, inflammatory
response to poststroke neurogenesis, and remodeling of the network. These changes and …