Combining experimental and computational techniques to understand and improve dry powder inhalers
ABSTRACT Introduction Dry Powder Inhalers (DPIs) continue to be developed to deliver an
expanding range of drugs to treat an ever-increasing range of medical conditions; with each …
expanding range of drugs to treat an ever-increasing range of medical conditions; with each …
Large eddy simulation study of the airflow characteristics in a human whole-lung airway model
Studying airflow characteristics in the human respiratory system is important for
understanding the properties of the aerosol transport and deposition. This study first …
understanding the properties of the aerosol transport and deposition. This study first …
Investigating unsteady airflow characteristics in the human upper airway based on the clinical inspiration data
To enhance understanding of the airflow characteristics in the human respiratory system
during realistic inspiration, we investigated the airflow field in a human upper airway model …
during realistic inspiration, we investigated the airflow field in a human upper airway model …
In vitro–in silico correlation of three-dimensional turbulent flows in an idealized mouth-throat model
There exists an ongoing need to improve the validity and accuracy of computational fluid
dynamics (CFD) simulations of turbulent airflows in the extra-thoracic and upper airways …
dynamics (CFD) simulations of turbulent airflows in the extra-thoracic and upper airways …
A review on numerical studies of airflow dynamics and particle deposition in human respiratory system
H Jing, X Cui - Particuology, 2024 - Elsevier
Accurate assessment and prediction of airflow dynamics and particle deposition in the
human respiratory tract are essential for human health, involving inhaled drugs for treating …
human respiratory tract are essential for human health, involving inhaled drugs for treating …
From μCT data to CFD: an open-source workflow for engineering applications
K Kuhlmann, C Sinn, JMU Siebert… - Engineering …, 2022 - Taylor & Francis
The generation of high-quality volume meshes out of µCT data can be a challenging task
that is mandatory to perform CFD simulations of fluid flows within or around scanned objects …
that is mandatory to perform CFD simulations of fluid flows within or around scanned objects …
A 3D printed human upper respiratory tract model for particulate deposition profiling
Pulmonary route is the main route of drug delivery for patients with asthma and chronic
obstructive pulmonary diseases, offering several advantages over the oral route …
obstructive pulmonary diseases, offering several advantages over the oral route …
Human upper-airway respiratory airflow: In vivo comparison of computational fluid dynamics simulations and hyperpolarized 129Xe phase contrast MRI velocimetry
Computational fluid dynamics (CFD) simulations of respiratory airflow have the potential to
change the clinical assessment of regional airway function in health and disease, in …
change the clinical assessment of regional airway function in health and disease, in …
Assessing airflow unsteadiness in the human respiratory tract under different expiration conditions
To enhance the understanding of airflow characteristics in the human respiratory system, the
expiratory airflow in a human respiratory tract model was simulated using large eddy …
expiratory airflow in a human respiratory tract model was simulated using large eddy …
Computational analysis of human upper airway aerodynamics
RHJ Hebbink, BJ Wessels, R Hagmeijer… - Medical & biological …, 2023 - Springer
There is a considerable interest in understanding transient human upper airway
aerodynamics, especially in view of assessing the effects of various ventilation therapies …
aerodynamics, especially in view of assessing the effects of various ventilation therapies …