Plasmepsins represent novel antimalarial drug targets. However, plasmepsin-based
antimalarial drug discovery efforts in the past 2 decades have generally suffered some …

The study of malaria parasites on the Indian subcontinent should help us understand
unexpected disease outbreaks and unpredictable disease presentations from Plasmodium …

Among the various parasitic diseases, malaria is the deadliest one. Due to the emergence of
high drug resistance to the existing drug candidates there is a global need for development …

Abstract Vivapain-3 (VP-3) protein is a family of cysteine rich proteases of malaria parasite is
extensively reported to participate in a range of wide cellular processes including survival …

Background Malaria continues to be one of the most severe global infectious diseases,
responsible for 1-2 million deaths yearly. The rapid evolution and spread of drug resistance …

Establishing an in vitro “red blood cell matrix” that would allow uninterrupted access to a
stable, homogeneous reticulocyte population would facilitate the establishment of …

Malaria parasites utilize Methylerythritol phosphate (MEP) pathway for synthesis of
isoprenoid precursors which are essential for maturation and survival of parasites during …

Introduction Plasmepsin V (PM-V) have functionally conserved orthologues across the
Plasmodium genus who's binding and antigenic processing at the PEXEL motifs for export …

The morphology of red blood cells is affected significantly during maturation of malaria
parasites, Plasmodium falciparum and Plasmodium vivax. A novel shape equation is …

In the present study, we investigated the genetic diversity of Plasmodium vivax metacaspase
1 (Pv MCA1) catalytic domain in two municipalities of the main malaria hotspot in Brazil, ie …