ER-phagy (reticulophagy) defines the degradation of portions of the endoplasmic reticulum
(ER) within lysosomes or vacuoles. It is part of the self-digestion (ie, autophagic) programs …

Research into the causes of psychopathology has largely focused on two broad etiologic
factors: genetic vulnerability and environmental stressors. An important role for …

Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …

Importance Anxiety and stress-related disorders are among the most common mental
disorders. Although family and twin studies indicate that both genetic and environmental …

Anxiety and fear are evolutionarily conserved emotions that increase the likelihood of an
organism surviving threatening situations. Anxiety and vigilance states are regulated by …

This review provides a broad overview of the state of research in the genetics of anxiety
disorders (AD). Genetic epidemiological studies report a moderate level of familial …

Extracellular vesicles (EVs) are present in numerous peripheral bodily fluids and function in
critical biological processes, including cell-to-cell communication. Most relevant to the …

Abstract Ca 2+-activated Cl− channels play important physiological roles in various cell
types, but their molecular identity is still unclear. Recently, members of the protein family …

Here we present a strategy to determine the genetic basis of variance in complex
phenotypes that arise from natural, as opposed to induced, genetic variation in mice. We …

The definitive resource for psychological diagnosis, updated with the latest research Adult
Psychopathology and Diagnosis offers comprehensive coverage of psychological disorders …