Retrotransposons are highly enriched in the animal genome,–. The activation of
retrotransposons can rewrite host DNA information and fundamentally impact host biology …

ABSTRACT A member of the Retroviridae, human immunodeficiency virus type 1 (HIV-1),
uses the RNA genome packaged into nascent virions to transfer genetic information to its …

HIV-1 reverse transcription is initiated from a tRNALys3 molecule annealed to the viral RNA
at the primer binding site (PBS). The annealing of tRNALys3 requires the opening of its three …

We have identified the tRNAs which are incorporated into both wild-type human
immunodeficiency virus type 1 strain IIIB (HIV-1IIIB) produced in COS-7 cells transfected with …

In all retroviruses, reverse transcription is primed by a tRNA whose 3'end 18 nucleotides are
complementary to the so called viral primer binding site. Previous work showed that reverse …

The ability of human immunodeficiency virus‐1 (HIV‐1) to undergo efficient reverse
transcription is dependent on a number of parameters. These include the binding of the …

Replication of the human immunodeficiency virus type 1 (HIV-1) and other retroviruses
involves reverse transcription of the viral RNA genome into a double-stranded DNA. This …

The genetic and functional basis of the replication-defective nature of human
immunodeficiency virus type 1 (HIV-1) in monkey cells was studied. By the generation and …

The initiation of human immunodeficiency virus type 1 (HIV-1) reverse transcription occurs at
a site in the viral RNA genome which is designated the primer-binding site (PBS). The HIV-1 …

The role of the RNA secondary structure in the 5'packaging signal region of human
immunodeficiency virus type 1 (HIV-1) in initiating translation of gag mRNA has been …