Histone modifications in Duchenne muscular dystrophy: pathogenesis insights and therapeutic implications

Y Wei, Y Jiang, Y Lu, Q Hu - Journal of Medical Genetics, 2024 - jmg.bmj.com
Duchenne muscular dystrophy (DMD) is a commonly encountered genetic ailment marked
by loss-of-function mutations in the Dystrophin gene, ultimately resulting in progressive …

Harnessing bioluminescence for drug discovery and epigenetic research

HJ Gleneadie, A Dimond, AG Fisher - Frontiers in Drug Discovery, 2023 - frontiersin.org
The naturally occurring phenomenon of bioluminescence has intrigued on-lookers for
decades and is now being developed as a powerful tool for medical research and preclinical …

Bioluminescence imaging of Cyp1a1-luciferase reporter mice demonstrates prolonged activation of the aryl hydrocarbon receptor in the lung

N Veland, HJ Gleneadie, KE Brown, A Sardini… - Communications …, 2024 - nature.com
Aryl hydrocarbon receptor (AHR) signalling integrates biological processes that sense and
respond to environmental, dietary, and metabolic challenges to ensure tissue homeostasis …