Subcortical serotonin 5HT2c receptor-containing neurons sex-specifically regulate binge-like alcohol consumption, social, and arousal behaviors in mice
ME Flanigan, OJ Hon, S D'Ambrosio, KM Boyt… - Nature …, 2023 - nature.com
Binge alcohol consumption induces discrete social and arousal disturbances in human
populations that promote increased drinking and accelerate the progression of Alcohol Use …
populations that promote increased drinking and accelerate the progression of Alcohol Use …
[HTML][HTML] The role of brain serotonin signaling in excessive alcohol consumption and withdrawal: A call for more research in females
ME Castle, ME Flanigan - Neurobiology of Stress, 2024 - Elsevier
Abstract Alcohol Use Disorder (AUD) is a leading cause of death and disability worldwide,
but current treatments are insufficient in fully addressing the symptoms that often lead to …
but current treatments are insufficient in fully addressing the symptoms that often lead to …
[HTML][HTML] Functional Adaptation in the Brain Habenulo–Mesencephalic Pathway During Cannabinoid Withdrawal
S Aroni, C Sagheddu, M Pistis, AL Muntoni - Cells, 2024 - mdpi.com
The mesolimbic reward system originating from dopamine neurons in the ventral tegmental
area (VTA) of the midbrain shows a profound reduction in function during cannabinoid …
area (VTA) of the midbrain shows a profound reduction in function during cannabinoid …
LPA1 receptors in the lateral habenula regulate negative affective states associated with alcohol withdrawal
Z Ren, J Hou, W Li, Y Tang, M Wang, R Ding… - …, 2023 - nature.com
The role of lysophosphatidic acid (LPA) signaling in psychiatric disorders and drug abuse is
significant. LPA receptors are widely expressed in the central nervous system, including the …
significant. LPA receptors are widely expressed in the central nervous system, including the …
Central Amygdala Astrocyte Plasticity Underlies GABAergic Dysregulation in Ethanol Dependence
TB Nentwig, JD Obray, A Kruyer, ET Wilkes… - …, 2024 - pmc.ncbi.nlm.nih.gov
Dependence is a hallmark of alcohol use disorder characterized by excessive alcohol intake
and withdrawal symptoms. The central nucleus of the amygdala (CeA) is a key brain …
and withdrawal symptoms. The central nucleus of the amygdala (CeA) is a key brain …
Modelling alcohol consumption in rodents using two-bottle choice home cage drinking and optional lickometry-based microstructural analysis
S Hou, NMA Soto, EJ Glover - bioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Two-bottle choice home cage drinking is one of the most widely used paradigms to study
ethanol consumption in rodents. In its simplest form, animals are provided with access to two …
ethanol consumption in rodents. In its simplest form, animals are provided with access to two …
Sex-specific regulation of binge drinking, social, and arousal behaviors by subcortical serotonin 5HT2c receptor-containing neurons
ME Flanigan, OJ Hon, S D'Ambrosio, KM Boyt… - bioRxiv, 2022 - biorxiv.org
Serotonin 5HT2c receptors have been implicated in the pathophysiology of both mood
disorders and alcohol use disorder, but the circuits mediating the effects of systemic …
disorders and alcohol use disorder, but the circuits mediating the effects of systemic …