Transcription factors of the forkhead box, class O (FoxO) family are important regulators of
the cellular stress response and promote the cellular antioxidant defense. On one hand …

The forkhead box O (FoxO) transcription factor family is a key player in an evolutionary
conserved pathway downstream of insulin and insulin-like growth factor receptors. The …

Aims: The N6-methyladenosine (m 6 A) modification plays an important role in various
biological processes, but its role in atherosclerosis remains unknown. The aim of this study …

Immune system defects are at the center of aging and a range of diseases. Here, we show
that prolonged fasting reduces circulating IGF-1 levels and PKA activity in various cell …

Forkhead box O (FOXO) transcription factors are central regulators of cellular homeostasis.
FOXOs respond to a wide range of external stimuli, including growth factor signaling …

Recent evidence suggests potential benefits from phytochemicals and micronutrients in
reducing the elevated oxidative and lipid‐mediated stress associated with inflammation …

Melatonin is an indoleamine that is synthesised from tryptophan under the control of the
enzymes arylalkylamine N‐acetyltransferase (AA‐NAT) and acetylserotonin …

Forkhead box protein O1 (FOXO1) is a transcription factor involved in various cellular
processes such as glucose metabolism, development, stress resistance, and tumor …

FOXO proteins are a sub-group of a superfamily of forkhead box (FOX)-containing
transcription factors (TFs). FOXOs play an important role in regulating a plethora of …

The growing worldwide prevalence of overnutrition and underexertion threatens the gains
that we have made against atherosclerotic cardiovascular disease and other maladies …