Synaptic dysfunction is closely related to Alzheimer's disease (AD) which is also recognized
as synaptic disorder. β-amyloid (Aβ) is one of the main pathogenic factors in AD, which …

Depression is one of the most prevalent and life-threatening forms of mental illnesses,
whereas Alzheimer's disease is a neurodegenerative disorder that affects more than 37 …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a progressive
deterioration of cognitive abilities, accumulation of the amyloid-β-peptide (Aβ) and synaptic …

Alzheimer's disease is associated with synapse loss, memory dysfunction, and pathological
accumulation of amyloid-β (Aβ) in plaques. However, an exclusively pathological role for Aβ …

Alzheimer's disease (AD) is an age-related neurological disorder characterized by synaptic
loss and dementia. The low-density lipoprotein receptor-related protein 6 (LRP6) is an …

The amyloid-β peptide (Aβ) plays a major role in neuronal dysfunction and neurotoxicity in
Alzheimer disease. However, the signal transduction mechanisms involved in Aβ-induced …

Microglia activation is central to the neuroinflammation associated with neurological and
neurodegenerative diseases, particularly because activated microglia are often a source of …

Abstract Alzheimer's disease (AD), a neurodegenerative disorder exhibiting a gradual
decline in cognitive function, is characterized by the presence of neuritic plaques composed …

In the past several years, we postulated that the loss of Wnt signaling was implicated in the
pathology of Alzheimer's disease (AD). Since then, our lab and other groups have confirmed …

Alzheimer's disease (AD) is the most common neurodegenerative disease, which severely
threatens the health of the elderly and causes significant economic and social burdens. The …